Tumour-Stroma Ratio as a Predictive Biomarker for Neoadjuvant Therapy Efficacy in Rectal Cancer.

Jonathan P Callaghan, Caroline R Cartlidge, Kenal Patel, Nicholas P West

Abstract readReview

In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan P CallaghanDivision of Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, Leeds LS9 7TF, UK.ORCID 0000-0001-7506-906X

Caroline R CartlidgeDivision of Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, Leeds LS9 7TF, UK.

Kenal PatelDivision of Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, Leeds LS9 7TF, UK.

Nicholas P WestDivision of Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, Leeds LS9 7TF, UK.ORCID 0000-0002-0346-6709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chemotherapycolorectal cancerimmunotherapyneoadjuvantpathological responsepredictive biomarkerradiotherapyrectal cancertumour cell densitytumour microenvironmenttumour–stroma ratio

Identifiers

PMID42449633

DOI10.3390/cancers18132089

PMCPMC13359533

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.