Evidence map›Paper›PMID 42449320›Full record

ArticleBMC oral health2026

A soft tissue-sparing positioning guide for the DCIA flap in mandibular reconstruction: a pilot study.

Jingcun Shi, Jieyu Wang, Ziqian Wu, Yuhan Zhang, Bingqing Zhang, Liwei Gu, Lei Wang

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jingcun Shi *Department of Stomatology, Fengcheng Hospital/Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Fengxian District, Shanghai, 201411, China.
Jieyu Wang *Department of Stomatology, Fengcheng Hospital/Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Fengxian District, Shanghai, 201411, China.
Ziqian WuDepartment of Oral and Maxillofacial Surgery - Head & Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China.
Yuhan ZhangDepartment of Oral and Maxillofacial Surgery - Head & Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University, Shanghai, 200011, China.
Bingqing ZhangShanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 201102, China.
Liwei GuDepartment of Stomatology, Fengcheng Hospital/Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Fengxian District, Shanghai, 201411, China.
Lei WangDepartment of Stomatology, Fengcheng Hospital/Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Fengxian District, Shanghai, 201411, China. wangleizyh@aliyun.com.

Funding

Development Fund for National Natural Science Foundation of Shanghai Jiaotong University School of Stomatology TSMS202501National Natural Science Foundation of China 81970907Shanghai Municipal Health Commission 202340135Special Fund for RCT of Shanghai Ninth People's Hospital JYXK-2026-002
6 · The paper itself

Abstract

backgroundPrecise placement of bone grafts is critical for functional and aesthetic outcomes in mandibular reconstruction. Conventional positioning guides typically require extensive stripping of periosteum and surrounding soft tissues, which may increase surgical trauma. This pilot study aimed to assess the feasibility and preliminary clinical performance of a novel soft tissue-sparing positioning guide for mandibular reconstruction.

methodsThis single-arm case series feasibility study included five female patients with segmental mandibular defects. Preoperative computed tomography data were used for virtual surgical planning and fabrication of patient-specific osteotomy and positioning guides using three-dimensional printing. The novel positioning guide featured an arched structural design that maintained a predefined clearance from the bone graft surface, allowing accommodation of periosteum and muscles while ensuring standardized and accurate fixation. Postoperative outcomes were evaluated using serial imaging and three-dimensional deviation analysis of six bilateral mandibular anatomical landmarks.

resultsAll patients completed the surgical protocol without flap loss or severe complications. Minor postoperative morbidity was limited to transient donor-site edema, and no permanent sensory deficits, local recurrence, or metastasis were observed during follow-up. Intraoperative findings confirmed effective preservation of soft tissues around the bone graft, except at the precision fixation part. Quantitative three-dimensional analysis demonstrated satisfactory postoperative mandibular alignment across all evaluated landmarks.

conclusionsThe proposed soft tissue-sparing positioning guide appears to be a feasible adjunct for mandibular reconstruction based on the findings of this preliminary study, but given that this is a small, uncontrolled feasibility case series, further validation in larger controlled studies is warranted.

Indexed as

Mandibular ReconstructionSurgical FlapsAdultBone TransplantationFeasibility StudiesFemaleHumansMiddle AgedOsteotomyPilot ProjectsPrinting, Three-DimensionalTomography, X-Ray ComputedBone transplantationDCIA flapMandibular osteotomyMandibular reconstructionPositioning guides

Identifiers

PMID42449320
PMCPMC13647663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.