ArticleBMC cardiovascular disorders2026
Association of lipid management-related knowledge, attitudes, and practices with LDL-C target attainment in patients with coronary heart disease: a multicenter cross-sectional study.
Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundLow-density lipoprotein cholesterol (LDL-C) target attainment remains suboptimal in patients with coronary heart disease (CHD). Patients' knowledge, attitudes, and practices (KAP) regarding lipid management may be associated with LDL-C control; however, evidence from Chinese populations remains limited.
methodsThis multicenter cross-sectional study included 520 patients with CHD from two hospitals in China. Lipid management-related KAP were assessed using a questionnaire developed specifically for this study. LDL-C target attainment was the outcome. Multivariable logistic regression and receiver operating characteristic analysis were performed.
resultsOverall, 22.5% of participants (117/520) achieved the LDL-C target. After adjustment for clinical covariates, attitude (OR = 1.136, 95% CI 1.076-1.203; P < 0.001) and practice (OR = 1.213, 95% CI 1.095-1.352; P < 0.001) remained significantly associated with LDL-C target attainment, whereas knowledge did not (OR = 1.013, 95% CI 0.878-1.172; P = 0.855). Adding KAP variables to the clinical model showed incremental within-sample discriminatory value for LDL-C target attainment, with the area under the curve increasing from 0.772 to 0.817 (P = 0.005).
conclusionsAmong Chinese patients with CHD, higher lipid management-related attitude and practice scores were significantly associated with LDL-C target attainment, whereas knowledge scores were not. KAP information showed incremental within-sample discriminatory value beyond the available clinical factors. Given the cross-sectional design, self-developed questionnaire, and lack of detailed lipid-lowering treatment information, these findings should be interpreted as exploratory associations rather than evidence of causal or clinically actionable determinants.
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