Evidence map›Paper›PMID 42449043›Full record

ArticleDermatology and therapy2026

A 6-Month Prospective, Open-Label, Randomized Study Showing Increased Hair Growth Rate in Women Using Multi-Targeting Hair Growth Nutraceuticals.

Rubaina Dang, Raja K Sivamani, Adina Hazan, Isabelle Raymond

Registry-linked trialAbstract read
In one paragraph

Article in Dermatology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06376409 (A Single-center, Prospective Study of Nutraceutical Supplements to Support Hair Growth in Females With Self-Perceived Thinning Hair), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06376409 nacompletednot on this map

A Single-center, Prospective Study of Nutraceutical Supplements to Support Hair Growth in Females With Self-Perceived Thinning Hair

TypeinterventionalSponsorNutraceutical Wellness Inc.Ran2024 to 2025Enrolled181ConditionsHair ThinningArmsNutrafol Women's Hair Growth Supplement, Nutrafol Women's Balance Hair Growth Supplement, Nutrafol Women's Vegan Hair Growth Supplement, Nutrafol Women's Postpartum Hair Growth Supplement
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rubaina DangIntegrative Research Institute, Sacramento, CA, USA.
Raja K SivamaniIntegrative Research Institute, Sacramento, CA, USA.ORCID http://orcid.org/0000-0001-7205-8162
Adina HazanNutraceutical Wellness, Inc., 236 5th Avenue, 7th Floor, New York, NY, 10001, USA.ORCID http://orcid.org/0009-0000-5051-3697
Isabelle RaymondNutraceutical Wellness, Inc., 236 5th Avenue, 7th Floor, New York, NY, 10001, USA. isabelle@nutrafol.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHair thinning is a multifactorial issue affecting women across life stages, frequently associated with reduced linear hair growth rate (LHGR). Hair growth nutraceuticals (HGNs) formulated with variations of a botanical-based multi-targeting complex are designed to address key root causes of hair thinning specific to different life stages. While prior studies have shown improvements in hair growth, quality, and fiber thickness, quantitative changes in LHGR have not been previously evaluated.

methodsThis prospective, 6-month study enrolled 180 women aged 18-70 years, assigned to one of four HGNs tailored for women at different life stages and diets. All subjects had self-reported hair thinning, confirmed by the study dermatologist. Participants were assessed at days 0, 90, and 180. Each timepoint included standardized hair clipping followed by objective analysis using Canfield HairMetrix

resultsA total of 150 participants completed the study per protocol. Daily ingestion of the tailored HGNs resulted in statistically significant increases in LHGR at both day 90 and day 180 compared with baseline across all four groups. Anagen hair counts rose significantly across the study duration in all groups, alongside gains in total and terminal hair counts. Total scalp coverage also significantly increased compared with baseline. The changes in hair parameters were corroborated with high agreement regarding improvements in hair parameters in the subject questionnaire.

conclusionsThis study demonstrates that consumption of these HGNs is associated with significant improvements in LHGR and other objective hair parameters in women experiencing hair thinning. These findings support the use of targeted HGNs as an effective strategy to enhance hair growth rate and overall hair health across different life stages.

trial registrationClinicalTrials.gov identifier: NCT06376409.

Indexed as

Hair countHair growth nutraceuticalsHair thinningLinear hair growth rate

Identifiers

PMID42449043
PMCPMC13558537

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