Evidence map›Paper›PMID 42448271›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2026

Associations of glyphosate exposure in pregnancy with preterm birth: a longitudinal birth cohort study.

Teresa Herrera, Fiona Fragoman, Akhgar Ghassabian, Whitney Cowell, Kim N Cajachagua Torres, Natasha Ard, Kurunthachalam Kannan, Zhongmin Li, Shilpi Mehta-Lee, Mengling Liu and 2 more

Abstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Teresa HerreraDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.
Fiona FragomanCase Western Reserve University School of Medicine, Cleveland, OH, United States.
Akhgar GhassabianDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States; Departments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States. Electronic address: akhgar.ghassabian@nyulangone.org.
Whitney CowellDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States; Departments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States.
Kim N Cajachagua TorresDepartments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States.
Natasha ArdDepartments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States.
Kurunthachalam KannanDepartments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States.
Zhongmin LiDepartments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States.
Shilpi Mehta-LeeDepartment of Obstetrics and Gynecology at NYU Grossman School of Medicine, New York, NY, United States.
Mengling LiuDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.
Heather H BurrisDepartment of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
Leonardo TrasandeDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States; Departments of Pediatrics, New York University Grossman School of Medicine, New York, NY, United States; New York University College of Global Public Health, New York City, NY, United States.

Funding

The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
The NYU Children’s Health & Environment Study: an ECHO CohortUG3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2016 to 2024
$26.5M
Developmental Origins of Kidney Function in Early Life and Environmental RisksR01ES032214 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MALAGA-DIEGUEZ, LAURA, TRASANDE, LEONARDO · 2020 to 2024
$3.5M
A Life-Course Approach to Assessing Effects of Environmental Exposures on Kidney DevelopmentR01ES036249 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Leonardo Trasande · 2025 to 2026
$1.7M
NIEHS NIH HHS R01 ES032214NIEHS NIH HHS R01 ES036249NIH HHS UG3 OD023305NIH HHS UH3 OD023305
6 · The paper itself

Abstract

backgroundEmerging data suggests that glyphosate, a non-selective herbicide, can influence reproductive health. We investigated associations of prenatal exposure to glyphosate and aminomethylphosphonic acid (AMPA), with preterm birth and its subtypes.

methodsWe used data from the NYU Children's Health and Environmental Study, a prospective birth cohort in New York City (2016-2019). Participants (n = 1450) provided urine samples at 4 to <18 weeks and 18 to 25 weeks gestation. Exposure was adjusted for creatinine and natural log transformed. Preterm birth was defined as a birth occurring before 37 weeks of gestation. We also explored preterm birth subtypes, spontaneous preterm births and medically indicated preterm births as secondary outcomes. To examine associations between glyphosate and AMPA at both timepoints with preterm birth, we used generalized estimating equations with a logit link function.

resultsOverall, 7% (n = 103) of births were preterm. Glyphosate concentrations at 18-25 weeks was associated with preterm birth (OR: 1.35, 95% CI: 1.04, 1.76) and spontaneous preterm birth (OR: 2.01, 95% CI: 1.40, 2.90). AMPA was not associated with preterm birth in any model.

conclusionsThese results support evidence that glyphosate may act upon pathways leading to preterm birth and spontaneous preterm birth. Our study highlights pregnancy as a vulnerable period to glyphosate exposure.

Indexed as

GlycineHerbicidesMaternal ExposurePremature BirthAdultBirth CohortFemaleGlyphosateHumansInfant, NewbornLongitudinal StudiesNew York CityOrganophosphonatesPregnancyProspective Studiesaminomethylphosphonic acid (AMPA)GlycineGlyphosateHerbicidesOrganophosphonatesBirth outcomesGestational ageGlyphosateHerbicidesPregnancyPreterm birth

Identifiers

PMID42448271
PMCPMC13564233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.