Evidence map›Paper›PMID 42448259›Full record

ArticleArchives of physical medicine and rehabilitation2026

Retrospective Analysis of the Relationship Between Poststroke Fatigue and Aphasia Severity.

Ellyn A Riley, Yina M Quique, Katarina L Haley, Adam Jacks, Jessica D Richardson

Abstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ellyn A RileyDepartment of Communication Sciences and Disorders, Syracuse University, Syracuse, NY. Electronic address: earil100@syr.edu.
Yina M QuiqueDepartment of Speech and Hearing Sciences, University of New Mexico, Albuquerque, NM.
Katarina L HaleyDivision of Speech and Hearing Sciences, Department of Health Sciences, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Adam JacksDivision of Speech and Hearing Sciences, Department of Health Sciences, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Jessica D RichardsonDepartment of Speech and Hearing Sciences, University of New Mexico, Albuquerque, NM.

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MCKENZIE, SAMUEL ARNOLD · 2015 to 2024
$22.7M
UNM FIRST: Promoting Inclusive Excellence in Neuroscience and Data Science - Administrative Supplement to support FIRST Faculty TravelU54CA272167 · NCI · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2022 to 2026
$20.4M
University of New Mexico (UNM) Center for Brain Recovery and RepairP30GM159568 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Lee Anna Cunningham · 2025 to 2026
$3.4M
Optimizing Targeted Interventions for Primary Progressive AphasiaR01DC018282 · NIDCD · UNIVERSITY OF NEW MEXICO · PI RICHARDSON, JESSICA D · 2021 to 2025
$3.1M
Pre-Frontal tDCS as a novel intervention to reduce effects of post-stroke fatigue while improving language and attention in aphasiaR01DC021677 · NIDCD · SYRACUSE UNIVERSITY · PI Ellyn Riley · 2025 to 2026
$1.5M
NCI NIH HHS U54 CA272167NIDCD NIH HHS R01 DC018282NIDCD NIH HHS R01 DC021677NIGMS NIH HHS P20 GM109089NIGMS NIH HHS P30 GM159568
6 · The paper itself

Abstract

objectivesTo characterize poststroke fatigue in people with aphasia and to investigate the relationship between aphasia severity and fatigue.

designCross-sectional observational design.

settingUniversity labs or clinic setting at 3 institutions in the United States, occasionally in participants' homes.

participantsAdults with chronic poststroke aphasia (N=73), with English reported as their primary language before stroke onset (mean age=59.4y; 61.6% men; mean time postonset=44.4mo). Aphasia severity, as measured by the Western Aphasia Battery-Revised (WAB-R), ranged from severe to very mild (scores of 14.7-100), with the majority (over 68%) presenting with mild-to-moderate impairment (scores 76-100).

interventionsNot applicable.

main outcome measuresThe WAB-R was used to measure aphasia severity (Aphasia Quotient). The Multidimensional Assessment of Fatigue measured poststroke fatigue using the Global Fatigue Index, consisting of 4 dimensions: severity, distress, interference, and timing.

resultsParticipants reported moderate ratings of fatigue across all Multidimensional Assessment of Fatigue dimensions, with substantial individual variability. Bayesian regression showed that higher WAB-R scores were associated with greater fatigue (β=0.31; 95% credible interval, 0.06-0.55), but age and sex were not.

conclusionsParticipants with milder aphasia reported greater poststroke fatigue than those with more severe impairments. These findings suggest that compensatory cognitive demands and elevated communication expectations that are associated with milder language deficits may contribute to increased fatigue burden. Results emphasize the need for routine fatigue screening across all aphasia severity levels and support reconceptualizing mild aphasia as potentially involving substantial hidden costs.

Indexed as

AphasiaFatigueRehabilitationStroke

Identifiers

PMID42448259
PMCPMC13675093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.