ArticleVascular biology (Bristol, England)2026
From mummies to internal mammaries: a historical perspective on the discovery of atherosclerosis.
Article in Vascular biology (Bristol, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to explore the historical evolution of atherosclerosis, from early understanding of the function of the heart and blood vessels to the discovery of arterial occlusive disease. This narrative review draws on historical medical texts, archaeological findings, and recent literature. It synthesizes developments in cardiovascular understanding across ancient, classical, and modern eras, with attention to changing paradigms. Evidence of atherosclerosis has been observed in mummified remains from ancient civilizations, predating any formal understanding of the cardiovascular system. In classical antiquity, the heart and vessels were often assigned symbolic or spiritual meaning, gradually giving way to empirical inquiry and anatomical study. Eventually, atherosclerosis came to be recognized as a multifactorial disease with significant clinical consequences. The understanding of atherosclerosis has evolved through centuries of speculation, anatomical discovery, and technological innovation. These perspectives provide a non-exhaustive overview of historical concepts of the cardiovascular system and atherosclerosis in particular.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.