Evidence map›Paper›PMID 42446937›Full record

ArticleDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2026

Efficacy and Safety of Balloon Endoscopy-Assisted Peroral Cholangiopancreatoscopy (POCPS) Using a Novel 9Fr Cholangioscope in Patients With Surgically Altered Anatomy: A Dual-Center Retrospective Study (With Video).

Haruka Toyonaga, Yuki Tanisaka, Makoto Masaki, Arata Oka, Akihiro Okita, Fumiya Osaki, Yoshiki Matsuno, Shoji Takayama, Hidetoshi Nakata, Takuya Takayama and 10 more

Abstract readMulticenter StudyVideo-Audio Media
In one paragraph

Article in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Haruka ToyonagaDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.ORCID https://orcid.org/0000-0001-7300-3665
Yuki TanisakaDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.
Makoto MasakiDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Arata OkaDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Akihiro OkitaDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Fumiya OsakiDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Yoshiki MatsunoDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Shoji TakayamaDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Hidetoshi NakataDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Takuya TakayamaDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Tatsuya NakagawaDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Masahiro OrinoDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Hironao MatsumotoDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.
Ryosuke HamamuraDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.
Ryuichi WatanabeDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.
Suguru ItoDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.
Akashi FujitaDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.ORCID https://orcid.org/0000-0001-9475-0512
Masafumi MizuideDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.
Shomei RyozawaDepartment of Gastroenterology, Saitama Medical University International Medical Center, Hidaka, Japan.
Masaaki ShimataniDepartment of Gastroenterology and Hepatology, Kansai Medical University Medical Center, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroral cholangiopancreatoscopy (POCPS) is established for diagnosis and treatment of pancreatobiliary diseases in patients with normal anatomy, but has been difficult to perform in patients with surgically altered anatomy (SAA) because conventional cholangioscope systems cannot pass through the working channel of balloon endoscopes. The novel 9Fr cholangioscope (eyeMAX 9Fr; Micro-Tech) has a 3.2-mm outer diameter, enabling passage through the 3.2-mm working channel of short-type balloon endoscopes and allowing through-the-channel POCPS during balloon endoscopy-assisted ERCP (BE-ERCP) without scope exchange. We retrospectively evaluated 38 consecutive BE-POCPS procedures using the eyeMAX 9Fr in patients with SAA at two tertiary centers in Japan. Indications included biliary stone (n = 31), pancreatobiliary stricture (n = 4), pancreatic stone (n = 1), cystic duct selection (n = 1), and migrated stent retrieval (n = 1). Technical success was achieved in all 38 cases (100%) across five reconstruction types using both single-balloon and double-balloon endoscopes. For lithotripsy (n = 32), stone fragmentation was successful in all cases, with single-session complete stone clearance in 53.1%. For stricture evaluation (n = 4), visual assessment-final diagnosis concordance was 75.0% (3/4) and biopsy adequacy rate was 75% (3/4); biopsy-final diagnosis concordance was 100% among adequate specimens (3/3). Adverse events occurred in three cases (7.9%), including lithotripsy-related bile duct mucosal injury/bleeding (n = 2), and scope-related small bowel perforation (n = 1). BE-POCPS using the eyeMAX 9Fr is a feasible and safe approach enabling direct visualization, targeted biopsy, and lithotripsy in SAA patients without scope exchange.

Indexed as

Biliary Tract DiseasesCholangiopancreatography, Endoscopic RetrogradeNatural Orifice Endoscopic SurgeryPancreatic DiseasesAdultAgedAged, 80 and overEquipment DesignFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomeballoon endoscopycholangioscopyelectrohydraulic lithotripsypancreatoscopysurgically altered anatomy

Identifiers

PMID42446937
PMCPMC13367453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.