Evidence map›Paper›PMID 42446788›Full record

SynthesisJournal of occupational rehabilitation2026

Return to Work and Employment Outcomes in Survivors of Differentiated Thyroid Cancer: A Systematic Review.

Anca-Maria Sirbu, Corina Oancea, Octavian-Mihai Sirbu, Anicuta Cernamoriti, Diana Loreta Paun

Abstract readSystematic Review
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In one paragraph

Synthesis in Journal of occupational rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anca-Maria SirbuDoctoral School, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Corina OanceaNational Institute of Expertise and Rehabilitation of Work Capacity, Bucharest, Romania. corina.oancea@umfcd.ro.
Octavian-Mihai SirbuFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. octavian-mihai.sirbu@drd.umfcd.ro.
Anicuta CernamoritiNational Institute of Expertise and Rehabilitation of Work Capacity, Bucharest, Romania.
Diana Loreta PaunFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDifferentiated thyroid cancer (DTC) predominantly affects individuals of working age and is characterized by excellent long-term survival. However, occupational recovery after treatment has received limited and fragmented attention in the literature. The objective is to systematically review the available evidence on return to work and employment-related outcomes among survivors of differentiated thyroid cancer.

methodsPubMed/MEDLINE, Scopus, and Web of Science Core Collection were searched from database inception to December 2025 in accordance with PRISMA guidelines. Observational and qualitative studies reporting work- or employment-related outcomes in adult DTC survivors were included. Given the substantial heterogeneity of study designs and outcome measures, a narrative synthesis was performed.

resultsTwenty-three studies met the inclusion criteria. Although many DTC survivors returned to work relatively early, incomplete occupational recovery was frequently reported, including reduced working hours, prolonged sick leave, income loss, or long-term employment difficulties. Work-related outcomes varied widely across studies and were influenced by nononcological factors such as fatigue, psychological distress, and sociodemographic characteristics. Importantly, several studies highlighted a mismatch between actual return to work and readiness to return to work, indicating that work resumption often occurred before full functional and psychological recovery.

conclusionsDespite excellent oncological outcomes, survivors of differentiated thyroid cancer may experience persistent challenges in employment. Return to work should be regarded as a multidimensional process rather than a binary outcome, highlighting the need for standardized assessment and targeted vocational support in survivorship care.

Indexed as

Cancer survivalDifferentiated thyroid cancerEmploymentReturn to workWork ability

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.