Evidence map›Paper›PMID 42446770›Full record

Trial reportHernia : the journal of hernias and abdominal wall surgery2026

Influence of internal ring defect closure on postoperative seroma formation after laparoscopic transabdominal preperitoneal repair for large indirect inguinal hernia: A randomized controlled study.

Mao Xiong, Wei-Hang Liu, Qi-Di Zhu, Bin Zhao, Li Zhu, Zhui Long

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Mao XiongDepartment of General Surgery, Chongqing Academy of Medical Sciences, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue Liangjiang New Area, Chongqing, 401147, China.
Wei-Hang LiuDepartment of General Surgery, Chongqing Academy of Medical Sciences, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue Liangjiang New Area, Chongqing, 401147, China.
Qi-Di ZhuDepartment of General Surgery, Chongqing Academy of Medical Sciences, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue Liangjiang New Area, Chongqing, 401147, China.
Bin ZhaoDepartment of General Surgery, Chongqing Academy of Medical Sciences, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue Liangjiang New Area, Chongqing, 401147, China.
Li ZhuDepartment of General Surgery, Chongqing Academy of Medical Sciences, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue Liangjiang New Area, Chongqing, 401147, China.
Zhui LongDepartment of General Surgery, Chongqing Academy of Medical Sciences, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue Liangjiang New Area, Chongqing, 401147, China. 18883369110@163.com.

Funding

Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission CSTB2023NSCQ-MSX1000
6 · The paper itself

Abstract

purposeTo evaluate the effect of internal ring defect closure on seroma prevention after laparoscopic transabdominal preperitoneal inguinal hernia repair (TAPP).

methodsWe conducted a randomized controlled trial including male patients aged 18-75 years with indirect inguinal hernia classified as L3 (defect ≥ 3 cm). Participants were randomly assigned to undergo TAPP with internal ring closure (DC group) or none closure (NC group). Primary outcomes were operative time and postoperative seroma incidence, assessed by clinical examination and ultrasonography at 7 days, 1 month, and 3 months. Secondary outcomes included postoperative pain, recurrence, hospital stay, and complications.

resultsA total of 76 patients were randomized (DC, n = 38; NC, n = 38). Baseline characteristics were comparable between groups. During the 90-day follow-up period, postoperative seroma occurred in 3 patients in the DC group and 10 patients in the NC group. Kaplan-Meier analysis demonstrated a significantly higher seroma-free survival rate in the DC group than in the NC group (log-rank P = 0.0335). No significant differences were observed in operative time, postoperative pain, length of hospital stay, recurrence, or other postoperative complications.

conclusionsInternal ring defect closure during TAPP repair significantly improves seroma-free survival and reduces the incidence of early postoperative seroma without increasing operative risk, postoperative pain, or morbidity.Although recurrence was not observed, the relatively small sample size and limited follow-up warrant cautious interpretation. Larger multicenter studies with extended surveillance are needed to validate these findings and define the role of internal ring closure in optimizing outcomes after laparoscopic inguinal hernia repair.

Indexed as

Hernia, InguinalHerniorrhaphyLaparoscopyPostoperative ComplicationsSeromaAdolescentAdultAgedHumansLength of StayMaleMiddle AgedOperative TimePostoperative PainRecurrenceSurgical MeshInguinal herniaInternal ring closureRandomized controlled trialSeromaTAPP

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.