Evidence map›Paper›PMID 42446657›Full record

ArticleMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents2026

Design, synthesis and insecticidal activities of novel meta-diamide compounds containing ethyl group.

Dong Li, Zhu Xia, Jiyong Liu, Juncheng Xiang, Qiqi Huang, Liang Lv, Hang Gong, Kangming Li

Abstract read
PubMed Publisher
In one paragraph

Article in Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pesticidal evaluation of novel dual-chiralJournal of enzyme inhibition and medicinal chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dong LiCollege of Chemistry, Xiangtan University, Xiangtan, China.
Zhu XiaCAC Nantong Chemical Co., Ltd, Nantong, China.
Jiyong LiuCAC Nantong Chemical Co., Ltd, Nantong, China.
Juncheng XiangCAC Nantong Chemical Co., Ltd, Nantong, China.
Qiqi HuangCAC Nantong Chemical Co., Ltd, Nantong, China.
Liang LvCAC Nantong Chemical Co., Ltd, Nantong, China.
Hang GongCollege of Chemistry, Xiangtan University, Xiangtan, China. hgong@xtu.edu.cn.
Kangming LiCAC Nantong Chemical Co., Ltd, Nantong, China. kangming_li@cacch.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To develop structurally novel and efficient insecticides, a series of ethylpyridine-containing meta-diamide derivatives were designed and synthesized using cyproflanilide as the lead compound. The core bioactive scaffold was retained while integrating active substructure combination and pharmacophore fusion strategies. All compounds were characterized by ¹H NMR, ¹³C NMR,

Indexed as

DiamideDrug DesignInsecticidesAnimalsMolecular StructureMothsStructure-Activity RelationshipTetranychidaeDiamideInsecticidesEthylpyridine；CyproflanilideInsecticidal activityMeta-diamide derivativesStructure-activity relationship.

Identifiers

PMID42446657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.