ArticleClinical neuroradiology2026
Clinical Feasibility of PETRA-MRA for Long-Term Surveillance of Clipped Intracranial Aneurysms: a Retrospective Single-Center Study in 546 Aneurysms.
Article in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the diagnostic capability and vessel visibility of Pointwise Encoding Time Reduction with Radial Acquisition MR angiography (PETRA-MRA) in a large cohort of patients with clipped intracranial aneurysms. MATERIALS AND
methodsThis retrospective single-center study included patients who underwent surgical clipping and follow-up MRI with PETRA-MRA sequence between January 2021 and August 2024. Two radiologists independently assessed PETRA-MRA and TOF-MRA for vessel visibility and recurrent aneurysms. Diagnostic performance was evaluated using DSA or CTA as reference standards.
resultsA total of 368 patients with 546 clipped intracranial aneurysms were evaluated (mean age, 64 ± 10.6 years; median follow-up, 8.9 years). Twenty recurrent aneurysms (3.7%; incidence 0.61% per patient-year) were identified. In the DSA/CTA-verified subset, PETRA-MRA detected 18 of 20 recurrent aneurysms (sensitivity, 90.0%), whereas TOF-MRA detected 7 of 19 (36.8%). PETRA-MRA demonstrated a specificity of 91.7%. For recurrent aneurysms smaller than 3 mm, PETRA-MRA detected more lesions than TOF-MRA (80.0% vs. 11.1%). Vessel visibility at the clipped aneurysm was higher in PETRA-MRA (72.3%) than TOF-MRA (12.5%). Interobserver agreement for PETRA-MRA was moderate (weighted κ = 0.51).
conclusionPETRA-MRA showed higher sensitivity and improved adjacent-vessel visualization compared with TOF-MRA in verified and strictly paired analyses. These findings suggest that PETRA-MRA may be a useful imaging tool for the postoperative surveillance of clipped intracranial aneurysms. Because reference-standard angiography was selectively performed, specificity, PPV, NPV, and accuracy should be interpreted as verified-subset estimates.
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