Evidence map›Paper›PMID 42446615›Full record

ArticleBiomolecular NMR assignments2026

Sayan Das, Jeffrey A Purslow, Kyle Malcom, Joshua Knott, Vincenzo Venditti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecular NMR assignments, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sayan DasDepartment of Chemistry, Iowa State University, Hach Hall, 2438 Pammel Drive, Ames, IA, 50011, USA.
Jeffrey A PurslowRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, 50,011, USA.
Kyle MalcomRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, 50,011, USA.
Joshua KnottRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, 50,011, USA.
Vincenzo VendittiDepartment of Chemistry, Iowa State University, Hach Hall, 2438 Pammel Drive, Ames, IA, 50011, USA. venditti@iastate.edu.ORCID https://orcid.org/0000-0001-8734-0400

Funding

Atomic-level characterization of self-regulatory mechanisms in large multidomain enzymesR35GM133488 · NIGMS · IOWA STATE UNIVERSITY · PI Vincenzo Venditti · 2019 to 2026
$2.9M
Console and Probe Upgrade for a 700 MHz NMR SpectrometerS10OD032235 · OD · IOWA STATE UNIVERSITY · PI ANDREOTTI, AMY H · 2022 to 2022
$1.0M
NIGMS NIH HHS R35 GM133488NIH HHS S10 OD032235
6 · The paper itself

Abstract

Protein and nucleic acid alkylation are important genetic and epigenetic modifications. The dynamic balance between alkylation and dealkylation is regulated by distinct sets of enzymes and is essential for maintaining genomic stability. Escherichia coli AlkB is a member of the Alkylation B (AlkB) family of dioxygenases that dealkylates a wide range of nucleic acid substrates in E. coli, thereby playing a crucial role in cellular repair processes and epigenetic regulation. Here, we report the backbone

Indexed as

AlkB EnzymesEscherichia coliEscherichia coli ProteinsKetoglutaric AcidsMixed Function OxygenasesNuclear Magnetic Resonance, BiomolecularZincAlkB EnzymesAlkB protein, E coliEscherichia coli ProteinsKetoglutaric AcidsMixed Function OxygenasesZincAlkB demethylasesAlkB dioxygenasesAlkylation BBackbone resonance assignmentTransverse relaxation optimized spectroscopy

Identifiers

PMID42446615
PMCPMC13369706

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.