Evidence map›Paper›PMID 42446541›Full record

ArticleMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents2026

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V R Akhmetova, D V Leont'ev, N S Akhmadiev, V N Perfilova, V S Sirotenko, E A Paramonov, I I Prokofiev, M A Sagalaev, V R Khairullina, D V Ishmetova and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

V R AkhmetovaInstitute of Petrochemistry and Catalysis, Ufa Federal Research Center of the Russian Academy of Sciences, 141, prosp. Oktyabrya, Ufa, 450075, Russia. vnirara@mail.ru.
D V Leont'evInstitute of Petrochemistry and Catalysis, Ufa Federal Research Center of the Russian Academy of Sciences, 141, prosp. Oktyabrya, Ufa, 450075, Russia.
N S AkhmadievInstitute of Petrochemistry and Catalysis, Ufa Federal Research Center of the Russian Academy of Sciences, 141, prosp. Oktyabrya, Ufa, 450075, Russia.
V N PerfilovaVolgograd State Medical University, 1, Pavshikh Bortsov Sq, Volgograd, 400131, Russia.
V S SirotenkoVolgograd State Medical University, 1, Pavshikh Bortsov Sq, Volgograd, 400131, Russia.
E A ParamonovInstitute of Petrochemistry and Catalysis, Ufa Federal Research Center of the Russian Academy of Sciences, 141, prosp. Oktyabrya, Ufa, 450075, Russia.
I I ProkofievVolgograd State Medical University, 1, Pavshikh Bortsov Sq, Volgograd, 400131, Russia.
M A SagalaevVolgograd State Medical University, 1, Pavshikh Bortsov Sq, Volgograd, 400131, Russia.
V R KhairullinaUfa University of Science and Technology, 32, Zaki Validi, Ufa, 450078, Russia.
D V IshmetovaInstitute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, 71, prosp. Oktyabrya, Ufa, 450054, Russia.
Yu V VakhitovaInstitute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, 71, prosp. Oktyabrya, Ufa, 450054, Russia.

Funding

State assignment of the Ministry of Science and Higher Education of the Russian Federation FMRS-2025-0041
6 · The paper itself

Abstract

Tricyclic 1-(3,4,5,6-tetrahydro-1H-[1,4,6]-thiadiazocino[4,3-a]-indol-12-yl)methanamides were synthesized as pyridine complexes using one-pot, four-component amino- and thiomethylation reactions of 1Н-indole with formaldehyde, secondary amines, and 1,2-aminothiol. C(sp

Indexed as

Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntineoplastic AgentsIndolesAnimalsCyclooxygenase 1Cyclooxygenase 2HumansMaleMethylationMiceMolecular Docking SimulationMolecular StructureOsteoarthritisRatsStructure-Activity RelationshipAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntineoplastic AgentsCyclooxygenase 1Cyclooxygenase 2Indolesaminothiolsanti-inflammatory activitycytotoxic activityformaldehydeindoleone-pot synthesis

Identifiers

PMID42446541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.