Evidence map›Paper›PMID 42446454›Full record

ArticleJACC. Case reports2026

Leaflet-to-Ring Edge-to-Edge Repair With Paravalvular Leak Closure for Dehisced Surgical Mitral Annuloplasty.

Prasham Dave, Alice Moroni, Kitae Kim, Abdulaziz Alshaibi, Robert Kay, Tasnim Vira, Neil P Fam

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prasham DaveStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Alice MoroniStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Kitae KimStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Abdulaziz AlshaibiStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Robert KayStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Tasnim ViraStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Neil P FamStructural Heart Program, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address: neil.fam@unityhealth.to.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous mitral valve repair after surgical annuloplasty is not well described but represents an important therapeutic option for patients with prohibitive risk for redo surgery. CASE SUMMARY: An 85-year-old man with symptomatic severe mitral regurgitation and hemolysis following prior mitral annuloplasty with a SimpliciT incomplete flexible band presented with anterior leaflet prolapse, a markedly deficient posterior leaflet, and posterior ring dehiscence. He underwent a combined percutaneous strategy of mitral transcatheter edge-to-edge repair (M-TEER) with anterior leaflet-to-annuloplasty ring clipping and paravalvular leak (PVL) closure using a vascular plug, resulting in reduction of mitral regurgitation from severe to mild-to-moderate and resolution of hemolysis. DISCUSSION: Annuloplasty ring dehiscence is generally considered unfavorable for transcatheter mitral valve replacement with current-generation devices, leaving limited percutaneous treatment options for patients with recurrent mitral regurgitation after surgery. This case demonstrates the feasibility of combining M-TEER with PVL closure to address complex mixed intravalvular and paravalvular regurgitation in high-risk patients. TAKE-HOME MESSAGES: Combined M-TEER and PVL closure is an effective solution for recurrent mitral regurgitation in selected patients with deficient leaflet anatomy and annuloplasty ring dehiscence when guided by careful imaging and multidisciplinary heart team planning.

Indexed as

annuloplastymitral regurgitationparavalvular leakTEER

Identifiers

PMID42446454
PMCPMC13531210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.