Evidence map›Paper›PMID 42446406›Full record

ArticleTranscription2026

Promoter contacts by TFB and TFEα during archaeal transcription initiation.

Michael Micorescu, Kimberly Sheffield, Vlad Geshka, Hannah Tierney, Michael S Bartlett

Abstract read
In one paragraph

Article in Transcription, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael MicorescuDepartment of Biology, Portland State University, Portland, OR, USA.
Kimberly SheffieldDepartment of Biology, Portland State University, Portland, OR, USA.
Vlad GeshkaDepartment of Biology, Portland State University, Portland, OR, USA.
Hannah TierneyDepartment of Biology, Portland State University, Portland, OR, USA.
Michael S BartlettDepartment of Biology, Portland State University, Portland, OR, USA.ORCID 0000-0001-5101-1832

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription initiation by archaeal RNA polymerase (RNAP) is assisted by transcription factors, TBP, TFB, and TFEα, which show sequence, structural and functional homology to eukaryotic TBP, TFIIB, and TFIIEα. Previous low-resolution cross-linking studies of transcription complexes from the hyperthermophile archaeon

Indexed as

Archaeal ProteinsPromoter Regions, GeneticPyrococcus furiosusTranscription Factors, TFIITranscription Factor TFIIBTranscription Initiation, GeneticDNA-Directed RNA PolymerasesModels, MolecularProtein BindingArchaeal ProteinsDNA-Directed RNA PolymerasesTranscription Factors, TFIITranscription Factor TFIIBtranscription factor TFIIEinitially transcribing complexpre-initiation complexprotein cross-linkingTFBTFEαtranscriptiontranscription initiation factor

Identifiers

PMID42446406
PMCPMC13502027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.