Evidence map›Paper›PMID 42446180›Full record

Trial reportHealth policy and planning2026

Evaluating the impact of conditional micro-incentives on linkage to HIV care in rural South Africa: results from the Home-Based Intervention to Test and Start (HITS) trial.

Hae-Young Kim, Maxime Inghels, Thulile Mathenjwa, Maryam Shahmanesh, Janet Seeley, Nuala McGrath, Oluwafemi Adeagbo, Dickman Gareta, H Manisha Yapa, Thembelihle Zuma and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Health policy and planning, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03757104 (Home-based Interventions to Test and Start), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03757104 naunknown statusnot on this map

Home-based Interventions to Test and Start (HITS): a Cluster-randomized Controlled Trial to Reduce Mortality and Incidence Through HIV Treatment

TypeinterventionalSponsorAfrica Health Research InstituteRan2018 to 2022Enrolled4,667ConditionsHIV, HIV Testing, Linkage to CareArmsmicro-incentive, EPIC-HIV, micro-incentive and EPIC-HIV
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hae-Young KimDepartment of Population Health, New York University Grossman School of Medicine, 180 Madison Avenue, New York, NY 10016, United States.ORCID 0000-0002-5124-1555
Maxime InghelsLincoln Institute for Rural and Coastal Health, University of Lincoln, Brayford Pool, Lincoln LN6 7TS, United Kingdom.
Thulile MathenjwaAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.
Maryam ShahmaneshAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.
Janet SeeleyAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.ORCID 0000-0002-0583-5272
Nuala McGrathAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.
Oluwafemi AdeagboDepartment of Sociology, University of Johannesburg, Johannesburg 2006, South Africa.
Dickman GaretaAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.
H Manisha YapaKirby Institute, University of New South Wales  Sydney, Level 6, Wallace Wurth Building, High Street, NSW 2052, Australia.
Thembelihle ZumaAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.
Adrian DobraUniversity of Washington, Box 354322, Seattle, Washington 98195, United States.
Till W BärnighausenAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.
Frank TanserAfrica Health Research Institute, 719 Umbilo Road, Durban 4001, KwaZulu-Natal, South Africa.ORCID 0000-0001-9797-0000

Funding

Causal Pathways to population health impact of HIV antiretroviral treatmentR01HD084233 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2015 to 2021
$2.3M
Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South AfricaR01AI124389 · NIAID · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2016 to 2020
$2.1M
The changing face of HIV in the era of COVID-19: Maximising HIV incidence reduction through dynamic targeting of current and future distributions of acquisition risk.R01MH131480 · NIMH · STELLENBOSCH UNIVERSITY · PI Henry Godwell Mwambi, Frank Courteney Tanser · 2023 to 2026
$2.0M
Engineering and Physical Sciences Research Council EP/K031953/1Engineering and Physical Sciences Research Council MRC MR/P024378/1Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD084233National Institute of Allergy and Infectious Diseases R01AI124389NIAID NIH HHS R01 AI124389NICHD NIH HHS R01 HD084233NIHR RP-2017-08-ST2-008NIMH NIH HHS R01 MH131480NIMH NIH HHS R01MH131480South African Medical Research CouncilWellcome TrustWellcome Trust 201433/A/16/A
6 · The paper itself

Abstract

Timely linkage from HIV diagnosis to care is critical for effective treatment and epidemic control. We evaluated the effectiveness of conditional micro-incentives on linkage to HIV care in the Home-Based Intervention to Test and Start (HITS) trial, a real-world implementation trial in rural South Africa. Of 45 communities in uMkhanyakude, KwaZulu-Natal, 16 were randomized to micro-incentive arms offering food vouchers (R50 [US$3]) conditional on completing home-based HIV counseling and testing (HBHCT) and linkage to care within 6 weeks, and 29 to non-incentive arms. All individuals were eligible for HBHCT, enrolled between February and December 2018, and followed for 1 year. The primary outcome was linkage to care at 1 year among men; secondary outcomes included linkage within the 6-week voucher eligibility period among men and women, and at 1 year among women. Intention-to-treat analyses were performed using Poisson regression adjusted for study arms. Among 13 894 men and 19 884 women eligible for the study (aged ≥15 years), home-based testing uptake was 21% (n = 2867) and 29% (n = 5795), yielding 122 (4.3%) and 375 (6.5%) new diagnoses, respectively. Overall, micro-incentives nearly doubled HIV-positive diagnoses. Among men, micro-incentives did not increase linkage to care within the 6-week voucher eligibility period (risk ratio [RR] = 0.78, 95% CI: 0.51-1.21) or at 1 year (RR = 1.08, 95% CI: 0.86-1.35). Among women, micro-incentives increased linkage to care within 6 weeks by 51% (RR = 1.51; 95% CI: 1.03-2.21), with no residual impact at 1 year (RR = 1.07, 95% CI: 0.91-1.26). In a hyperendemic rural African setting, once-off micro-incentives can substantially increase early linkage to HIV care among women during the incentive eligibility period but are inadequate to significantly improve care engagement among men. Trial Registration  ClinicalTrials.gov NCT03757104.

Indexed as

HIV InfectionsHome Care ServicesAdultFemaleHIV TestingHumansMaleRural PopulationSouth Africalinkage to HIV caremicro-incentivesrandomized controlled trialSouth Africa

Identifiers

PMID42446180
PMCPMC13678824

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.