Evidence map›Paper›PMID 42446092›Full record

ArticleJournal of food science2026

Biological Safety and Functional Properties of Açaí Seed Extract: Antioxidant Capacity and Prebiotic Potential.

Marcelo Pereira da Silva Junior, Amanda de Jesus Alves Miranda, Ana Laura Gagliardi, Isabelle Guerreiro Moreira, Maria Eduarda Santos Camaceti, Mateus Kawata Salgaço, Kátia Sivieri, Cláudia Quintino da Rocha, Flávia Aparecida Resende

Abstract read
In one paragraph

Article in Journal of food science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcelo Pereira da Silva JuniorDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0009-0008-9398-2643
Amanda de Jesus Alves MirandaDepartment of Chemistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, Brazil.
Ana Laura GagliardiDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0009-0001-5401-4075
Isabelle Guerreiro MoreiraDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0009-0006-5066-5782
Maria Eduarda Santos CamacetiDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0009-0009-7356-9680
Mateus Kawata SalgaçoDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.
Kátia SivieriDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.
Cláudia Quintino da RochaDepartment of Chemistry, Federal University of Maranhão (UFMA), São Luís, Maranhão, Brazil.ORCID https://orcid.org/0000-0002-3578-1869
Flávia Aparecida ResendeDepartment of Biological Sciences and Health, University of Araraquara (UNIARA), Araraquara, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-9432-5919

Funding

Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorFundação de Amparo à Pesquisa do Estado de São Paulo
6 · The paper itself

Abstract

Açaí (Euterpe oleracea) is widely recognized as a functional food due to its nutritional value and abundance of bioactive compounds. Its seeds, representing approximately 80%-95% of the fruit mass, constitute an abundant agro-industrial byproduct with promising biotechnological potential. This study aimed to chemically characterize a 70% ethanolic extract obtained from E. oleracea seeds through liquid chromatography-mass spectrometry (LC-MS) annotation and total phenolic content (TPC) determination, as well as to investigate its antioxidant activity, prebiotic potential, cytotoxicity, and mutagenic safety profile. The extract was obtained by percolation using 70% ethanol. Antioxidant activity was evaluated by the DPPH assay, while prebiotic potential was assessed through submerged in vitro fermentation with Lactiplantibacillus plantarum LP90, monitoring bacterial growth and medium acidification. Cytotoxicity was evaluated in Caco-2 cells using a resazurin assay, and mutagenicity was investigated using the micronucleus and Ames tests. LC-MS annotation revealed a phenolic-rich profile, mainly composed of procyanidins. The extract showed a TPC of 123.12 ± 5.70 mg GAE/g dry weight and significant antioxidant activity (EC

Indexed as

AntioxidantsEuterpePlant ExtractsPrebioticsSeedsCaco-2 CellsFermentationHumansLactiplantibacillus plantarumPhenolsAntioxidantsPhenolsPlant ExtractsPrebioticsaçaíbiological propertiesEuterpe oleraceaplant extractstoxicological evaluation

Identifiers

PMID42446092
PMCPMC13367018

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.