Evidence map›Paper›PMID 42445902›Full record

ArticleFrontiers in public health2026

Development and validation of a questionnaire to assess environmental and lifestyle factors influencing infectious disease outcomes: application to SARS-CoV-2-infected individuals in Cuba.

Waldemar Baldoquín-Rodríguez, Ana B Pérez, Lizette Gil, Rosario Gravier, Hector Granela, Odalys Orraca, Lillyam Betancourt-Peraza, Alejandro Almeida-Pons, Juan M Junco-Rodriguez, Pablo Sariol and 7 more

Abstract readValidation Study
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Waldemar Baldoquín-Rodríguez *Center for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Ana B PérezCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Lizette GilCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Rosario GravierCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Hector GranelaCellular, Molecular, and Biomedical Sciences, University of Vermont, Burlington, VT, United States.
Odalys OrracaOutpatient Department, Clíníca Central Cira García, Havana, Cuba.
Lillyam Betancourt-PerazaCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Alejandro Almeida-PonsCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Juan M Junco-RodriguezMedical Attention Center, Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Pablo SariolMedical Attention Center, Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Tatiana PrietoMedical Attention Center, Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Dennis PérezCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Veerle VanlerbergheDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
María G GuzmánCenter for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.
Wim Vanden BergheDepartment of Biomedical Sciences (BMW), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences (FBD), Cell Death Signaling Lab, University of Antwerp, Antwerp, Belgium.
Xaveer Van OstadeDepartment of Biomedical Sciences (BMW), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences (FBD), Cell Death Signaling Lab, University of Antwerp, Antwerp, Belgium.
Beatriz Sierra *Center for Research, Diagnostic and Reference (CIDR), Pedro Kourí Institute of Tropical Medicine (IPK), Havana, Cuba.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: The coronavirus disease 2019 (COVID-19) pandemic highlighted the influence of behavioral and environmental factors on the risk of infection, as well as on disease progression and severity. Therefore, it is critical to improve public health knowledge regarding the factors influencing disease outcomes. This study describes the development and validation of the "Cuban population environmental and lifestyle factors Questionnaire" (CELF-Q), a tool designed to evaluate the impact of environmental and lifestyle factors on COVID-19 outcomes in the Cuban population. Study design and setting: Based on an existing lifestyle questionnaire developed for the Latin American population, a thorough process of modification, cross-cultural adaptation, and iterative desk review was conducted to generate the CELF-Q. Pre-test analysis was performed to assess face and content validity. To evaluate content validity, a panel of 15 experts was selected. Test-retest reliability was assessed in 60 participants, while internal consistency was evaluated by administering the questionnaire to 309 individuals with SARS-CoV-2 infection. Confirmatory factor analysis (CFA) was performed to assess the fit of the CELF-Q's factor structure. Results: The content validity of the questionnaire was deemed "acceptable" across several dimensions, based on the results of the content validity ratio (CVR), content validity index (CVI), and Aiken's validity (V). Only a few items were identified for revision using these quantitative measures. Additionally, the experts supplemented the evaluations with qualitative comments for the modification of the questions. The test-retest reliability analysis showed an overall mean kappa coefficient of 0.89 [standard deviation (SD): 0.21] and a mean overall correlation coefficient of 0.99 (0.02), indicating high to almost perfect agreement. An internal consistency analysis showed that the majority of the dimensions had acceptable Cronbach's alpha values. In particular, the self-care behavior, socioeconomic restrictions, and diet and nutritional habits dimensions achieved respectable Cronbach's alpha values (between 0.7 and 0.8). Conclusion: The generated CELF-Q is a comprehensive, valid, and reliable tool for obtaining information on environmental/lifestyle factors associated with SARS-CoV-2 infection, as well as the development and severity of COVID-19, in the Cuban population.

Indexed as

COVID-19EnvironmentLife StyleAdultCubaFemaleHumansMaleMiddle AgedReproducibility of ResultsSARS-CoV-2Surveys and Questionnairesclinical outcomeCOVID-19environmental factorshabitslifestylevalidation

Identifiers

PMID42445902
PMCPMC13357406

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.