Evidence map›Paper›PMID 42445815›Full record

ReviewJournal of experimental orthopaedics2026

Management of moderate pain after orthopaedic surgery: A multiregional expert consensus model for postoperative and discharge protocol development.

Gabriele Finco, Giovanni Balato, Carlo Busatto, Gaetano Caruso, Alessandro Colosio, Antonio Coviello, Valerio Daffara, Pasquale De Negri, Alessandro Donà, Silvia Ferri and 20 more

Abstract readReview
In one paragraph

Review in Journal of experimental orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Gabriele FincoDepartment of Medical Sciences and Public Health University of Cagliari Cagliari Italy.
Giovanni BalatoDepartment of Orthopaedic Surgery and Traumatology University of Naples "Federico II" Naples Italy.
Carlo BusattoDepartment of Orthopaedic Surgery and Traumatology Santa Maria delle Croci Hospital Ravenna Italy.
Gaetano CarusoDepartment of Orthopaedic Surgery and Traumatology, AOU Ferrara Arcispedale Sant'Anna University of Ferrara Ferrara Italy.
Alessandro ColosioDepartment of Orthopaedic Surgery and Traumatology Casa di Cura Città di Parma Parma Italy.
Antonio CovielloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences University of Naples "Federico II" Naples Italy.
Valerio DaffaraDepartment of Orthopaedic Surgery and Traumatology Spedali Civili Brescia Italy.
Pasquale De NegriDepartment of Anesthesia Intensive Care and Pain Medicine, AORN S.Anna & S. Sebastiano Caserta Italy.
Alessandro DonàDepartment of Orthopaedic Surgery and Traumatology, Sassuolo Hospital University of Modena and Reggio Emilia Sassuolo Italy.
Silvia FerriDepartment of Anesthesia Intensive Care and Pain Medicine, Casa di Cura Città di Parma Parma Italy.
Olimpio GalassoDepartment of Orthopaedic Surgery and Traumatology, AOU San Giovanni di Dio e Ruggi d'Aragona University of Salerno Fisciano Italy.
Giovanni GasbarroDepartment of Anesthesia Postoperative Intensive Care and Pain Medicine, IRCCS Rizzoli Orthopaedic Institute Argenta Ferrara Italy.
Federico Alberto GrassiDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences University of Pavia Pavia Italy.
Massimo InnamoratoDepartment of Neuroscience AUSL Romagna, Pain Unit, Santa Maria Delle Croci Hospital Ravenna Italy.
Mattia LoppiniDepartment of Orthopaedic Surgery and Traumatology IRCCS Humanitas Research Hospital Rozzano Milano Italy.
Maria Benedetta MasciaDepartment of Anesthesia Intensive Care and Pain Medicine, IRCCS Policlinico San Matteo Foundation Pavia Italy.
Anna Maria MatinaDepartment of Anesthesia, Intensive Care and Pain Medicine, AOU Ferrara Arcispedale Sant'Anna University of Ferrara Ferrara Italy.
Carlo Francesco MinoliUOC Week Surgery, ASST Gaetano Pini-CTO Milan Italy.
Paolo PernaDepartment of Neuroscience AUSL Romagna, Pain Unit, Santa Maria Delle Croci Hospital Ravenna Italy.
Giacomo PlacellaUniversità Vita-Salute San Raffaele Milan Italy.
Elena PriscoDepartment of Anesthesiology, TIPO e OTI Antonio Cardarelli Hospital Naples Italy.
Laura Ramponi1st Orthopaedic and Traumatologic Department IRCCS Istituto Ortopedico Rizzoli Bologna Italy.
Nicola SbalzerDepartment of Anaesthesia and Intensive Care Spedali Civili di Brescia Brescia Italy.
Pasquale SangiovanniDepartment of Orthopaedic Surgery and Traumatology Antonio Cardarelli Hospital Naples Italy.
Pasquale SansoneDepartment of Women, Child and General and Specialized Surgery University of Campania "Luigi Vanvitelli" Naples Italy.
Francesco TassoDepartment of Anesthesia Intensive Care and Pain Medicine, IRCCS Humanitas Research Hospital Rozzano Milano Italy.
Andrea TognùDepartment of Anesthesia Intensive Care and Pain Medicine, ASST Gaetano Pini-CTO Milan Italy.
Giuseppe ToroDepartment of Medical and Surgical Specialties and Dentistry University of Campania "Luigi Vanvitelli" Naples Italy.
Giulia TorselloDepartment of Anesthesia Intensive Care and Pain Medicine, Sassuolo Hospital Italy.
Alberto Di Martino1st Orthopaedic and Traumatologic Department IRCCS Istituto Ortopedico Rizzoli Bologna Italy.ORCID https://orcid.org/0000-0002-0716-4951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moderate post-operative pain after orthopaedic surgery remains highly prevalent and frequently persists beyond hospital discharge, negatively impacting mobilisation, rehabilitation, patient satisfaction and risk of chronic post-surgical pain. Despite established multimodal analgesic strategies, clinical pathways remain heterogeneous and insufficiently standardised. The objective was to develop a shared, reproducible, and implementable model for the management of moderate post-operative pain in orthopaedic surgery, both during hospitalisation and at discharge, to support institutional protocol development. An adapted virtual Nominal Group Technique (vNGT) was used as a structured consensus methodology. Three regional expert panels were convened in Campania, Lombardia and Emilia Romagna. Before each meeting, panellists completed a structured pre-meeting survey and received preparatory material. Each meeting followed pre-defined vNGT stages: introduction and framing of the consensus questions, individual idea generation, structured round-robin sharing, clarification and refinement of statements, completion of standardised decision tables and post-meeting review/acceptance of the synthesised framework. Survey responses and decision tables were analysed qualitatively and comparatively to identify convergent principles, setting-specific operational variables, and reproducible components. A reproducible model emerged based on systematic pain assessment, defined analgesic targets, multimodal analgesia centred on scheduled non-opioid therapy, integration of loco-regional techniques, rational, rescue based opioid use, structured continuity of care at discharge. Setting specific declinations were defined for: (1) Day surgery and Arthroscopy, (2) major trauma surgery in the elderly, (3) lower limb arthroplasty surgery and (4) discharge management across all settings. This vNGT-derived framework provides an implementable structure for institutional pain management protocols in orthopaedic surgery and represents a foundation for future outcome-based validation studies. Level of Evidence: Level N/A.

Indexed as

ibuprofenmultimodal analgesiaorthopaedic surgeryparacetamolpost‐operative pain

Identifiers

PMID42445815
PMCPMC13361057

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.