ReviewFrontiers in cell and developmental biology2026
Dual regulation of autophagy: paradoxical effects on tumor angiogenesis.
Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The Role of Traditional Chinese Medicine in Acute Lung Injury: Targeting Programmed Cell Death.Drug design, development and therapy · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autophagy plays a critical role in dynamic cell growth under different environmental conditions and maintains cellular homeostasis and cell viability in response to different cellular injuries, especially in tumor angiogenesis, where there is a controversial dual role. Angiogenesis plays a key role in facilitating tumor development. Therefore, investigating the mechanism of action of autophagy in the flexible shift of tumor angiogenesis is essential for antiangiogenic clinical therapy, and modulating the autophagy process is expected to constitute a new strategy to inhibit tumor angiogenesis and stop tumor growth and spread. This review highlights the close connection between autophagy and tumor angiogenesis. We also attempt to explain the seemingly contradictory promotion or inhibition of angiogenesis in tumor development reported in past studies. We focus on the potential clinical value of autophagy agonists and inhibitors in antiangiogenic therapy, which will provide new theoretical bases for antitumor therapy and may lead to innovative therapeutics.
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Registered trials
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