Evidence map›Paper›PMID 42445596›Full record

ArticleBioinformatics advances2026

TelomereHunter2: improved

Ferdinand Popp, Nicola Biondi, Urška Pogorevčnik, Nicholas Abad, Chen Hong, Yoann Pageaud, Benedikt Brors, Lars Feuerbach

Abstract read
In one paragraph

Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ferdinand PoppDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.ORCID https://orcid.org/0000-0003-3833-5052
Nicola BiondiDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
Urška PogorevčnikDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
Nicholas AbadDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
Chen HongDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
Yoann PageaudDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
Benedikt BrorsDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.ORCID https://orcid.org/0000-0001-5940-3101
Lars FeuerbachDivision Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: Telomere biology plays a critical role in multiple biological processes including carcinogenesis, aging, and genome stability. With increasing availability of DNA-sequence datasets, telomere length and composition are more frequently directly inferred Results: We developed TelomereHunter2 (TH2) to create a sustainable framework for telomere analysis. By containerizing our software and improving the runtime by up to 74%, we simplify the integration of TH2 into diverse precision oncology workflows and computational environments. We also extended TH2 to support non-human genomes and single-cell sequencing approaches, broadening its applications across species and methodologies. We demonstrate TH2 improvements on a pilot dataset. Availability and implementation: TelomereHunter2 is an open-source Python package released under the GPL-3.0 license. It is distributed via PyPI and the source code, documentation, and wiki are available at: https://github.com/ferdinand-popp/TelomereHunter2.

Indexed as

BioinformaticsComputational GenomicsNext-Generation SequencingSequence AnalysisTelomeres

Identifiers

PMID42445596
PMCPMC13361702

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.