ArticleFrontiers in pediatrics2026
Preliminary epidemiological and clinical profile of the 2024 pediatric pertussis outbreak: a retrospective analysis.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In 2024, a global surge in pediatric pertussis cases emerged, deviating from traditional clinical patterns. This outbreak was characterized by atypical symptoms and increased hospitalization rates. This study aimed to characterize the epidemiological and clinical features of children hospitalised with pertussis during the outbreak in the Fuzhou region of China and to identify predictors of prolonged hospitalization. Methods: We performed a retrospective analysis of PCR-confirmed pediatric pertussis cases admitted to Fuzhou Second General Hospital in 2024. We evaluated demographics, clinical signs, lab results, and treatment. Univariable and multivariable linear regression analyses were performed to identify factors associated with hospitalization duration. Additional LASSO regression analysis was performed as a sensitivity analysis. Results: A total of 69 children with PCR-confirmed pertussis were included in the analysis. In 2024, the pertussis outbreak began in April, peaked in June-July, and declined by August. Infants and preschool-aged children bore the highest disease burden, with a notable incidence in school-aged children. Unexpectedly, prolonged hospitalization correlated with the absence of fever and normal inflammatory markers. Multivariate analysis identified elevated platelet counts ( Conclusions: In this retrospective study of children hospitalised with pertussis during the 2024 Fuzhou outbreak, infants and school-aged children were disproportionately affected, with a seasonal distribution. Prolonged hospital stays were linked to afebrile presentations with normal inflammatory markers, while elevated platelet counts and ALT levels may predict extended hospitalization. These findings may offer useful reference points for clinical risk stratification, though validation in larger multicenter prospective studies is warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.