Evidence map›Paper›PMID 42445503›Full record

ArticlemicroLife2026

Interferon-stimulated gene 15 expression negatively regulates resistance to

Jördis V Schuchardt, Alexis Urtecho Valverde, Beatriz Cristóvão, Marina Pekmezović, Raquel Alonso-Roman, Mark S Gresnigt

Abstract read
In one paragraph

Article in microLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jördis V SchuchardtJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745 Jena, Thuringia, Germany.ORCID https://orcid.org/0009-0008-2879-462X
Alexis Urtecho ValverdeJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745 Jena, Thuringia, Germany.
Beatriz CristóvãoJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745 Jena, Thuringia, Germany.ORCID https://orcid.org/0000-0002-9655-0984
Marina PekmezovićJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745 Jena, Thuringia, Germany.ORCID https://orcid.org/0000-0003-1991-9634
Raquel Alonso-RomanJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745 Jena, Thuringia, Germany.ORCID https://orcid.org/0000-0002-7020-5613
Mark S GresnigtJunior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745 Jena, Thuringia, Germany.ORCID https://orcid.org/0000-0002-3277-7522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vulvovaginal candidiasis (VVC) is one of the most common fungal infections, affecting most women during their reproductive years. A core characteristic of VVC is the interplay between

Indexed as

Epithelial thresholdInterferon-stimulated gene 15Interferon βType I interferon responseVulvovaginal candidiasisZ-DNA binding protein 1

Identifiers

PMID42445503
PMCPMC13359237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.