Evidence map›Paper›PMID 42445423›Full record

ArticleTranslational cancer research2026

KLK6 regulates ferroptosis through YAP/TAZ in lung adenocarcinoma.

Junyu Xu, Xinran Xi, Xun Wu, Zhongbo Yu, Xiaoao Yin, Xianghai Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junyu XuDepartment of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Xinran XiDepartment of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Xun WuDepartment of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Zhongbo YuDepartment of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Xiaoao YinDepartment of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Xianghai WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of lung adenocarcinoma (LUAD) has increased in recent years. Kallikrein related peptidase 6 (KLK6), a member of the serine protease family, is found to be aberrantly overexpressed in various solid tumors. This gene functions as a driver of tumor progression, mediating growth, invasion and migration through diverse mechanisms. This study aimed to explore how Methods: We utilized The Cancer Genome Atlas (TCGA) (https://www.cancer.gov/ccg/research/genome-sequencing/tcga) and Western blot analysis to assess Results: Conclusions: The experimental results show that knocking down

Indexed as

ferroptosisKallikrein related peptidase 6 (KLK6)lung adenocarcinoma (LUAD)prognosisYes-associated protein (YAP)

Identifiers

PMID42445423
PMCPMC13357092

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.