Evidence map›Paper›PMID 42445411›Full record

ReviewTranslational cancer research2026

Micro- and nanoplastic exposure and cancer: current evidence, mechanistic pathways, and translational challenges.

Yuxin Han, Zihan Chen, Zizhou Zhang, Xiaolan Lv, Yue Han, Liubing Hou, Xiaoying Xue, Huandi Zhou

Abstract readReview
In one paragraph

Review in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuxin HanDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0006-0941-1879
Zihan ChenDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Zizhou ZhangDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0007-1706-9249
Xiaolan LvDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yue HanDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Liubing HouDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0003-2018-8103
Xiaoying XueDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0002-4934-2904
Huandi ZhouDepartment of Radiotherapy, The Second Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0002-2617-6157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastics and nanoplastics are emerging contaminants widely detected in water, soil, air, food, and a range of human biological samples. Their potential implications for cancer biology have recently attracted growing interest at the interface of environmental health, toxicology, and oncology. Available evidence suggests that micro- and nanoplastic exposure may be associated with several solid tumors and certain hematological malignancies, and may influence tumor-related processes through oxidative stress, chronic inflammation, DNA damage and repair dysregulation, microbiota disturbance, metabolic reprogramming, and alterations in the immune microenvironment. However, the current evidence base remains limited and heterogeneous, relying predominantly on

Indexed as

cancerenvironmental exposureMicroplasticsmolecular mechanismsnanoplastics

Identifiers

PMID42445411
PMCPMC13357093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.