ArticleTranslational cancer research2026
Identification of exhausted CD8
Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Background: Multiple myeloma (MM) exhibits an exhausted CD8 Methods: Single-cell RNA sequencing (scRNA-seq) and RNA-seq data were downloaded, and the MM immune landscape was observed. Through differential expression analysis and weighted gene co-expression network analysis, differential exhausted CD8 Results: Thirteen DETGs that were mainly involved in tumor-related pathways were selected. Among these DETGs, JunD proto-oncogene (JUND) and nuclear factor kappa B inhibitor alpha (NFKBIA) correlated strongly with MM survival and immune response. Hence, these genes were considered as effective prognostic genes in MM and used to construct a prognostic risk score model. The risk score model exhibited promising predictive ability on MM survival. JUND and NFKBIA expression levels in the cell communication pseudo-temporal analysis were synchronous with CD8 Conclusions: A novel exhausted CD8
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