Evidence map›Paper›PMID 42445243›Full record

ArticleFrontiers in pharmacology2026

An integrated network toxicology and multi-omics study identifies ENO1 as a candidate mediator in benzo[a]pyrene-related gastric cancer progression.

Haixia Liu, Binru Di, Xiaoding Men, Jingzhou Zhu, Yaowen Liu, Jing Luo, Jianmei Wang, Li Xiang, Yuhao Luo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haixia Liu *Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Binru Di *Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Xiaoding MenDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Jingzhou ZhuDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yaowen LiuDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Jing LuoDepartment of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Jianmei WangDepartment of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Li XiangDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Yuhao LuoDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study employed an integrative toxicogenomic and multi-omics prioritization approach, combined with preliminary

Indexed as

alpha-enolase (ENO1)benzo[a]pyrenegastric cancermachine learningnetwork toxicologytumor microenvironment

Identifiers

PMID42445243
PMCPMC13357143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.