ArticleFrontiers in immunology2026
Case Report: Functional characterization of lymphocyte populations in a pediatric patient with WHIM syndrome.
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
WHIM syndrome is a rare primary immunodeficiency disorder caused by gain-of-function mutations of the chemokine receptor CXCR4, leading to abnormal and exacerbated leukocyte trafficking. It is associated with severe neutropenia and lymphopenia, and recurrent infections. Few pediatric cases have been reported, but comprehensive analyses of the composition and function of peripheral lymphocyte populations in pediatric WHIM syndrome are lacking. Here we report the case of a 6-year-old male patient carrying a
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