Evidence map›Paper›PMID 42445131›Full record

ArticleJournal of nutrition and metabolism2026

The TyG Index and Obesity Indicators Predicting Low Muscle Mass in US Adults Without Diabetes: NHANES 2011-2018.

Jiaqi Huo, Fang Li, Ting Wang, Simiao Tang, Yue Xi, Genqing Xie

Abstract read
In one paragraph

Article in Journal of nutrition and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jiaqi HuoDepartment of Clinical Nutrition, The First People's Hospital of Xiangtan City, Xiangtan, 411100, Hunan, China.ORCID https://orcid.org/0009-0009-0332-8953
Fang LiHunan Center for Evidence-Based Medicine, Clinical Epidemiology Laboratory, the Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China, csu.edu.cn.ORCID https://orcid.org/0000-0003-3564-3631
Ting WangDepartment of Clinical Nutrition, The First People's Hospital of Xiangtan City, Xiangtan, 411100, Hunan, China.ORCID https://orcid.org/0009-0006-9899-1739
Simiao TangDepartment of Clinical Nutrition, The First People's Hospital of Xiangtan City, Xiangtan, 411100, Hunan, China.ORCID https://orcid.org/0009-0006-9221-8518
Yue XiDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510275, Guangdong, China, sysu.edu.cn.ORCID https://orcid.org/0000-0001-9461-9303
Genqing XieDepartment of Clinical Nutrition, The First People's Hospital of Xiangtan City, Xiangtan, 411100, Hunan, China.ORCID https://orcid.org/0009-0002-7361-7071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Insulin resistance and obesity are critical determinants of low muscle mass. The main goal was to determine whether the reduced muscle mass in people without diabetes is correlated with the insulin resistance index and obesity indicators. Method: The data from NHANES 2011 to 2018 were analyzed to explore how the TyG index and obesity indices relate to low muscle mass. Associations were conducted using weighted logistic regression, RCS analysis, sensitivity analyses, and subgroup evaluations. In addition, the prediction capability of these indices was evaluated using ROC curve analysis and the AUC. Result: The TyG index (OR = 1.86, 95% CI: 1.31-2.63, Conclusion: The risk of insufficient muscle mass is increased in nondiabetic adults with higher values of TyG-obesity indicators (TyG-WC, TyG-WHtR, and TyG-WWI). TyG-WHtR possessed the best discriminative ability than other indicators.

Indexed as

insulin resistancelow muscle massobesityTyG index

Identifiers

PMID42445131
PMCPMC13359029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.