ArticleGland surgery2026
Point of care ultrasonography (POCUS) for assessment and intervention of thyroid nodules in an office setting.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background: Traditionally, thyroid ultrasounds and fine-needle biopsy have been performed by trained radiologist or sonographer. More recently, portable office-based point of care ultrasonography (POCUS) have been used in management of thyroid nodules. This study aims to compare the diagnostic accuracy and interventional performance of POCUS with conventional hospital-based console ultrasound in management of thyroid nodules. Methods: This is a retrospective case study set in a large community-based Otolaryngology practice with a dedicated thyroid ultrasound clinic. All patients referred to the thyroid clinic between January 2023 and December 2024 for ultrasound-guided fine-needle biopsy were assigned American College of Radiology Thyroid Imaging Reporting and Data System (TI-RADS) category in a prospective manner by the operator immediately prior to biopsy. Studies and procedures were performed utilizing a GE (General Electric Company) Healthcare Versana Active portable ultrasound with a 12 Hz linear probe (12L-RS). Hospital assigned TI-RADS categories were subsequently obtained through a retrospective chart review of the radiologist report. The performance of both the TI-RADS categories was compared. The Bethesda system for Reporting Thyroid Cytopathology (BSRTC Categories) was utilized for all cytology reports. Results: A total of 339 nodules underwent biopsy, of which 293 had available data for both the in-office and radiologist-assigned TI-RADS. Only the nodules with cytological categories of BSRTC categories of 2 through 6 were included in the study. The POCUS TI-RADS categories yielded a sensitivity of 1.00, specificity of 0.00, positive predictive value (PPV) of 0.10, and negative predictive value (NPV) of 1.00. The hospital-based radiologist TI-RADS categories yielded a sensitivity of 0.80, specificity of 0.35, PPV of 0.12, and NPV of 0.94. Sensitivity was significantly higher with the POCUS TI-RADS categories (P=0.01), while specificity was significantly higher with the hospital-based radiologist TI-RADS categories (P<0.001). Conclusions: In-office POCUS is a reliable diagnostic tool that offers high sensitivity in identifying malignant thyroid nodules in an in-office setting.
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