Evidence map›Paper›PMID 42445016›Full record

ArticleACS medicinal chemistry letters2026

Ligand-Engineered Cu(II) Complexes Suppress Stemness and Drug Resistance in Triple-Negative Breast Cancer.

Vemavarapu Durga Prasad, Suriya Panneerselvam, Jyotirmoy Dutta, Arpan Bera, Tukki Sarkar, Sai Balaji Andagulapati, Bathini Nagendra Babu

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vemavarapu Durga PrasadDepartment of Fluoro-Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.
Suriya PanneerselvamDepartment of Applied Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.
Jyotirmoy DuttaDepartment of Chemistry, Handique Girls' College, Guwahati, Assam 781001, India.
Arpan BeraDepartment of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India.ORCID https://orcid.org/0000-0001-8271-5285
Tukki SarkarDepartment of Fluoro-Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.ORCID https://orcid.org/0000-0002-7852-4344
Sai Balaji AndagulapatiDepartment of Applied Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.ORCID https://orcid.org/0000-0002-7591-737X
Bathini Nagendra BabuDepartment of Fluoro-Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Telangana, India.ORCID https://orcid.org/0000-0001-7378-0878

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is an aggressive malignancy characterized by cancer stem cell (CSC) enrichment and multidrug resistance. Here, we report a series of Cu-(II) complexes (

Indexed as

cancer stem cellscopper(II) complexesdrug resistanceligand engineeringtriple-negative breast cancer

Identifiers

PMID42445016
PMCPMC13358962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.