Evidence map›Paper›PMID 42444987›Full record

ArticleFrontiers in aging neuroscience2026

The amino acid substitutions A30W, K28A, and M35C alter amyloid-β peptide toxicity in cell culture and in an

Diana Patricia Quijano-Guerrero, Ana Esther Estrada-Rodríguez, Mauricio Caballero-Rodríguez, Danna Loretta de León-Rivera, Cristina Rodríguez-Padilla, Victor Julian Valdes, Diana Caballero-Hernández, Román Vidaltamayo, Ana Carolina Martínez-Torres, Viviana Zomosa-Signoret

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diana Patricia Quijano-GuerreroLaboratorio de Inmunología y Virología, Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico.
Ana Esther Estrada-RodríguezSchool of Medicine, University of Monterrey (UDEM), San Pedro Garza García, Nuevo León, Mexico.
Mauricio Caballero-RodríguezSchool of Medicine, University of Monterrey (UDEM), San Pedro Garza García, Nuevo León, Mexico.
Danna Loretta de León-RiveraSchool of Medicine, University of Monterrey (UDEM), San Pedro Garza García, Nuevo León, Mexico.
Cristina Rodríguez-PadillaLaboratorio de Inmunología y Virología, Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico.
Victor Julian ValdesDepartment of Cell Biology and Development, Institute of Cellular Physiology (IFC), National Autonomous University of Mexico (UNAM), Mexico City, Mexico.
Diana Caballero-HernándezLaboratorio de Inmunología y Virología, Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico.
Román VidaltamayoSchool of Medicine, University of Monterrey (UDEM), San Pedro Garza García, Nuevo León, Mexico.
Ana Carolina Martínez-TorresLaboratorio de Inmunología y Virología, Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico.
Viviana Zomosa-SignoretSchool of Medicine, University of Monterrey (UDEM), San Pedro Garza García, Nuevo León, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The buildup of toxic aggregates formed by the amyloid-β peptide 1-42 (Aβ

Indexed as

Alzheimer’s diseaseamyloid pathologyamyloid-β peptideamyloid-β variantsCaenorhabditis elegans

Identifiers

PMID42444987
PMCPMC13357907

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.