ArticleFrontiers in oncology2026
An integrative coding and non-coding SNPs analysis of the
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: By creating intramembrane tight-junction barriers, claudin-3 ( Methods: In this study, Results and discussion: Using SIFT, PolyPhen-2, and SNPs&GO, we first assessed 140 non-synonymous SNPs (nsSNPs). Out of these, 29 were consistently predicted as high-priority pathogenic by all three tools. Stability analysis based on ΔΔG using I-Mutant 2.0 and MUpro identified six corensSNPs that were stabilized after mutation and were predicted to impair protein function by MutPred2. Among them, N140I and Y147C lie near the Conclusion: These comprehensively identified
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