Evidence map›Paper›PMID 42444494›Full record

ArticleJournal of genetics2026

Ramakanth Chirravuri-Venkata, Aneek Das Bhowmik, Malini Nemalikanti, Suryanarayan Mishra, Bishwadeep Singha, Valli Undamatla, Chandreswara Raju Kataru, Shrey A, Ramyasri Kola, Divya Tej Sowpati and 2 more

Abstract readCase Reports
PubMed
In one paragraph

Article in Journal of genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ramakanth Chirravuri-VenkataCentre for Cellular and Molecular Biology, Habsiguda, Uppal Road, Hyderabad 500 007, India. karthikt.ccmb@csir.res.in.
Aneek Das Bhowmik
Malini Nemalikanti
Suryanarayan Mishra
Bishwadeep Singha
Valli Undamatla
Chandreswara Raju Kataru
Shrey A
Ramyasri Kola
Divya Tej Sowpati
Prajnya Ranganath
Karthik Bharadwaj Tallapaka

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic variations in DNA checkpoint kinases, cell cycle regulation, and DNA-damage repair genes are responsible for hereditary cancer predisposition. In a woman with a history of multiple primary cancers (carcinoma rectum and papillary carcinoma of thyroid) at a young age, whole exome sequencing (WES) of the blood revealed a likely pathogenic germline variation NM_001161346.2(CHFR):c.1231C[T (ClinVar variation ID: 1802254) in the

Indexed as

Genetic Predisposition to DiseaseNeoplasm ProteinsPoly-ADP-Ribose Binding ProteinsCell Cycle ProteinsExome SequencingFemaleGerm-Line MutationHumansUbiquitin-Protein LigasesCell Cycle ProteinsCHFR protein, humanNeoplasm ProteinsPoly-ADP-Ribose Binding ProteinsUbiquitin-Protein Ligases

Identifiers

PMID42444494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.