ArticleJournal of Korean medical science2026
Impact of Kidney Function on the Treatment Effect of Multi-Arterial Grafting in CABG Patients.
Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
backgroundThe adoption of multi-arterial grafting (MAG) remains limited in real-world coronary artery bypass grafting (CABG) practice. This study aimed to identify subsets of patients most likely to benefit clinically from MAG, and to explore potential effect modifiers of its treatment benefit, including renal function.
methodsThis retrospective cohort study analyzed 3,244 isolated CABG patients from a prospectively maintained institutional registry (2006-2020). Patients were categorized into MAG (n = 1,868) and single-arterial grafting (SAG; n = 1,376) groups. Inverse probability treatment weighting was applied to adjust for baseline differences, and Cox proportional hazards models evaluated overall survival. Subgroup analyses assessed interactions between treatment effects and patient characteristics, particularly estimated glomerular filtration rate (eGFR).
resultsOver a median follow-up of 7.1 years, MAG demonstrated significantly higher overall survival compared to SAG (
conclusionMAG offers significant survival advantages for CABG patients with relatively preserved renal function (eGFR ≥ 51). Renal function should thus be considered when selecting arterial grafting strategies to optimize patient outcomes.
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