ArticleAnnals of medicine2026
Gait asymmetry across frailty-status groups in older adults: clinical and biomechanical evidence from 3D gait analysis.
Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGait asymmetry is a sensitive marker of age-related neuromuscular dysfunction, but its multidimensional profiles across frailty stages remain unclear. This study characterized spatiotemporal, kinematic, and kinetic gait asymmetry across frailty-status groups.
methodsA total of 150 older adults (Non-frail = 49, Prefrail = 80, Frail = 21) underwent 3D gait analysis. Fifty-one gait asymmetry features spanning spatiotemporal parameters, joint kinematics, and kinetics were derived. Group differences were examined using Kruskal-Wallis tests and pairwise Mann-Whitney U tests with Benjamini-Hochberg false discovery rate (FDR) correction.
resultsNine of 51 features showed at least one significant pairwise difference after within-feature FDR adjustment. Compared with non-frail participants, prefrail participants exhibited greater asymmetry in single-support time (
conclusionsGait asymmetry differed across frailty-status groups. Prefrail participants mainly showed feature-level differences in spatiotemporal asymmetry, whereas frail participants showed additional feature-level differences involving hip/knee kinematic and knee kinetic asymmetry. These findings describe exploratory, domain-informed gait asymmetry patterns associated with frailty status. These cross-sectional associations require longitudinal validation before prognostic or clinical monitoring utility can be inferred.Trial registration: Chinese Clinical Trial Registry, ChiCTR2300073905.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.