ArticlePharmacotherapy2026
Comparison of Bayesian and First-Order Estimations of Vancomycin Area Under the Curve in Pediatrics Using One- and Two-Concentration Methods.
Article in Pharmacotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent consensus guidelines recommend therapeutic drug monitoring of vancomycin to target a 24-h area under the curve (AUC
methodsThis was a single center retrospective review of hospitalized pediatric patients receiving intravenous vancomycin. Patients with two concentrations collected at steady-state within 96 h of vancomycin initiation were screened. Pharmacokinetic parameters and AUC
resultsOverall, 196 patients (22 neonates, 17 infants, 114 children, and 43 adolescents) were included in the final analysis. Reasonable agreement was observed between linear and Bayesian two-concentration methods (84.2%; R
conclusionsLinear and Bayesian two-concentration methods demonstrated reasonable agreement with acceptable variability and may be considered comparable for estimating vancomycin AUC
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