Evidence map›Paper›PMID 42443986›Full record

ReviewJournal of eating disorders2026

Mental health interventions for carers of individuals with eating disorders: a systematic review of randomized controlled trials assessing efficacy on anxiety and depressive symptoms.

Ilaria Riboldi, Chiara Alessandra Capogrosso, Cristina Crocamo, Alessandro Chinello, Luigi Enrico Zappa, Francesco Bartoli, Giuseppe Carrà

Abstract readReview
In one paragraph

Review in Journal of eating disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilaria RiboldiSchool of Medicine and Surgery, University of Milano-Bicocca, via Cadore 48, 20900, Monza, Italy. ilaria.riboldi@unimib.it.
Chiara Alessandra CapogrossoSchool of Medicine and Surgery, University of Milano-Bicocca, via Cadore 48, 20900, Monza, Italy.
Cristina CrocamoSchool of Medicine and Surgery, University of Milano-Bicocca, via Cadore 48, 20900, Monza, Italy.
Alessandro Chinello18.56 Monitor Lab, Fondazione Maria Bianca Corno, via Zucchi 1, 20900, Monza, Italy.
Luigi Enrico Zappa18.56 Monitor Lab, Fondazione Maria Bianca Corno, via Zucchi 1, 20900, Monza, Italy.
Francesco BartoliSchool of Medicine and Surgery, University of Milano-Bicocca, via Cadore 48, 20900, Monza, Italy.
Giuseppe CarràSchool of Medicine and Surgery, University of Milano-Bicocca, via Cadore 48, 20900, Monza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarers of individuals with eating disorders (EDs) often experience high levels of psychological distress, which can lead to anxiety and depressive symptoms. While several interventions have been developed to support carers, the effectiveness on their mental health remains unclear.

methodsWe performed a systematic review of randomized controlled trials (RCTs) assessing mental health interventions for carers of individuals with EDs, with anxiety and depressive symptoms defined as outcomes of interest. Searches were performed across major electronic databases up to 31 October 2025.

resultsTwelve RCTs met the inclusion criteria. Structured narrative synthesis indicated that statistically significant effects were infrequent, outcome-specific, and generally small in magnitude. Interventions based on the Cognitive-Interpersonal Maintenance Model (CIMM) were the most frequently evaluated. However, only one trial demonstrated significant improvements in depressive symptoms (p = 0.010), with no significant effect on the Depression Anxiety Stress Scale (DASS-21) total scores (p = 0.06) or on the anxiety subscale (p = 0.50). In addition, Cognitive Behavioural Therapy (CBT)-based interventions showed some promising effects on the Hospital Anxiety and Depression Scale (HADS) total score (p = 0.033), but these results were not consistently replicated across guided and unguided formats. Among the other approaches, a video-based skills-training intervention produced a measurable reduction in carer distress, but this effect was observed only when combined with professional support (p = 0.030). Overall, interventions incorporating professional or peer support appeared more promising than fully self-directed approaches, although direct comparisons between guided and unguided formats did not consistently show statistically significant differences. Quality assessment showed at least an average standard of quality for all the included trials.

conclusionsInterventions for carers of individuals with EDs are conceptually well-founded, yet current evidence provides only limited support for their effectiveness in reducing anxiety and depressive symptoms. Future research should prioritize interventions that combine more structured mental health strategies with guided self-help programmes and workshops, providing tailored support to address the various needs of carers.

Indexed as

AnxietyCarerDepressionEating disordersMental health interventions

Identifiers

PMID42443986
PMCPMC13647608

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.