Evidence map›Paper›PMID 42443866›Full record

ArticleBMC oral health2026

Yeungyeung Liu, Yingxin Li, Bingyu Ran, Xiaoling Cao, Qijun Cai, Yong Cheng, Bin Guo, Jian Gong, Jingjie Shang, Hao Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yeungyeung Liu *Department of Periodontology, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, Guangdong, 510280, China.
Yingxin Li *Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Bingyu RanDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Xiaoling CaoDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Qijun CaiDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Yong ChengDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Bin GuoDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Jian GongDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China.
Jingjie ShangDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China. shangjj@jnu.edu.cn.
Hao XuDepartment of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China. txh@jnu.edu.cn.

Funding

Science research cultivation program of stomatological hospital, Southern medical university PY2023042
6 · The paper itself

Abstract

backgroundThe loss of alveolar bone in periodontitis is linked to ferroptosis mediated by Transferrin Receptor 1 (TfR1). This study employed a multimethod approach integrating in vitro and in vivo experiments to investigate the utility of gallium-68 citrate (

methodsIn vitro, MC3T3-E1 were stimulated with Porphyromonas gingivalis lipopolysaccharide (LPS) to model the inflammatory microenvironment. The correlation between TfR1 expression and

resultsIn vitro, LPS dose-dependently reduced MC3T3-E1 viability while upregulating TfR1 and IL1β, and downregulating GPX4 expression.

conclusionOsteoblast exhibited increased

Indexed as

CitratesFerroptosisGalliumGallium RadioisotopesPeriodontitisPositron Emission Tomography Computed TomographyReceptors, TransferrinAlveolar Bone LossAnimalsMaleMiceRatsRats, Sprague-DawleyCitratesGalliumgallium citrateGallium RadioisotopesReceptors, Transferrin68Ga-citrateFerroptosisMolecular imagingPeriodontitisTfR1

Identifiers

PMID42443866
PMCPMC13656373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.