Hip range of motion is differentially associated with pain sensitivity in individuals with and without knee osteoarthritis.

Isabela Lima Nóbrega, Marialice Gyaraki da Silva, Filipe Estevão Sette, Natalia Aparecida Casonato, Roberta Freitas Tizziotti, Stela Marcia Mattiello

Abstract readComparative Study

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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Isabela Lima NóbregaDepartment of Physical Therapy, Federal University of São Carlos, Rod. Washington Luís, s/n - Monjolinho, São Paulo, São Carlos, Brasil. isabelanobrega@estudante.ufscar.br.ORCID https://orcid.org/0009-0004-2440-076X

Marialice Gyaraki da SilvaDepartment of Physical Therapy, Federal University of São Carlos, Rod. Washington Luís, s/n - Monjolinho, São Paulo, São Carlos, Brasil.ORCID http://orcid.org/0000-0003-2121-3104

Filipe Estevão SetteDepartment of Physical Therapy, Federal University of São Carlos, Rod. Washington Luís, s/n - Monjolinho, São Paulo, São Carlos, Brasil.ORCID http://orcid.org/0009-0002-5839-9977

Natalia Aparecida CasonatoDepartment of Physical Therapy, Federal University of São Carlos, Rod. Washington Luís, s/n - Monjolinho, São Paulo, São Carlos, Brasil.ORCID http://orcid.org/0000-0003-4973-6249

Roberta Freitas TizziottiDepartment of Physical Therapy, Federal University of São Carlos, Rod. Washington Luís, s/n - Monjolinho, São Paulo, São Carlos, Brasil.ORCID http://orcid.org/0009-0003-3755-6467

Stela Marcia MattielloDepartment of Physical Therapy, Federal University of São Carlos, Rod. Washington Luís, s/n - Monjolinho, São Paulo, São Carlos, Brasil. stela@ufscar.br.ORCID http://orcid.org/0000-0001-9484-8026

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 20/16684-0

6 · The paper itself

Abstract

backgroundKnee osteoarthritis (KOA) is a multifactorial condition influenced by both mechanical and neurophysiological factors. Hip joint mobility may be associated to knee joint loading and pain processing; however, the relationships between hip range of motion (ROM), pain sensitivity, and muscle torque in individuals with KOA remain unclear. This study aimed to investigate the association between knee pain sensitivity and hip rotator ROM in individuals with and without KOA. Additionally, it examined the association between hip rotation ROM and muscle torque and compared hip ROM between groups.

methodsThis cross-sectional comparative study included 38 participants (26 with KOA and 12 healthy controls). A comprehensive physical assessment was conducted, including evaluation of both hip and knee range of motion (ROM) across multiple hip movements (flexion, extension, abduction, adduction, and internal and external rotation), measured using a digital inclinometer and a universal goniometer. Hip muscle torque was assessed using isokinetic dynamometry. Pain sensitivity was evaluated through Quantitative Sensory Testing, including pressure pain threshold (PPT), temporal summation (TS), and conditioned pain modulation (CPM). Group comparisons were performed using analysis of covariance (ANCOVA). Multiple linear regression models were used to examine the association between hip rotational ROM and pain sensitivity, including interaction terms for group.

resultsNo significant differences in hip or knee ROM were observed between groups. However, a significant interaction between total hip rotation and group was found for PPT at the knee joint line (p = 0.039; adjusted R

conclusionsThe association between hip ROM and pain sensitivity appears to differ according to the presence of KOA. These findings suggest that proximal mobility may be differentially related to pain sensitivity measures depending on clinical status, supporting the need for further investigation into hip-related factors in individuals with KOA.

Indexed as

ArthralgiaHip JointOsteoarthritis, KneePain ThresholdRange of Motion, ArticularAdultAgedCross-Sectional StudiesFemaleHumansKnee JointMaleMiddle AgedPain MeasurementTorqueHipKneeOsteoarthritisPainRange of motion

Identifiers

PMID42443848

DOI10.1186/s12891-026-10127-1

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