Observational studyBMC neurology2026
Effects of a staged postoperative blood pressure management protocol on cerebral perfusion stability and neurological outcomes after carotid artery stenting: a retrospective observational study.
Observational study in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCarotid artery stenting (CAS) carries a risk of postoperative cerebral perfusion instability. This study evaluated a multidisciplinary staged blood pressure (BP) management protocol on cerebral hemodynamics and neurological outcomes.
methodsRetrospective analysis included 67 CAS patients: control group (n = 33) received conventional BP management; intervention group (n = 34) received staged BP protocol. Cerebral hemodynamics were assessed using transcranial Doppler (TCD), including middle cerebral artery mean flow velocity (MCA-Vm) and pulsatility index (PI). Baseline, 24 h, 48 h, and 72 h values were recorded. Preoperative MRI/MRA were reviewed for impaired perfusion surrogates. NIHSS and Barthel Index (BI) were evaluated.
resultsIntervention group showed more stable MCA-Vm and PI. MCA-Vm peaked at 24 h (72.3 ± 14.8 cm/s) then stabilized or decreased to 64.8 ± 10.4 cm/s at 72 h. PI decreased from 0.94 ± 0.18 to 0.86 ± 0.14 in the intervention group versus 0.92 ± 0.21 to 0.78 ± 0.19 in controls. Fewer BP target failures occurred (17.6% vs. 45.5%; P = 0.019), and rescue antihypertensive therapy was less frequent (17.6% vs. 42.4%; P = 0.034). NIHSS at discharge was lower (1 [IQR 1-3] vs. 3 [2-4]; P = 0.009) and BI at 30 days higher (91.5 ± 7.6 vs. 84.3 ± 10.4; P = 0.002). A small subset exhibited postoperative MCA-Vm reduction, indicating heterogeneous hemodynamic responses.
conclusionStaged postoperative BP management was associated with stable TCD-derived cerebral hemodynamics and improved neurological outcomes after CAS. Findings reflect surrogate hemodynamic changes rather than absolute cerebral blood flow, emphasizing individualized, monitored BP management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.