Evidence map›Paper›PMID 42443799›Full record

ArticleBMC infectious diseases2026

Clinical and molecular characterizations of carbapenem-resistant Klebsiella pneumoniae among children with bloodstream infections in Beijing, China.

Jing Li, Zexuan Song, Wenjian Xu, Lin Zhou, Li Yu, Meng Tian, Xin Zhang, Lijuan Ma

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Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing LiDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Zexuan SongDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Wenjian XuDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Lin ZhouDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Li YuDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Meng TianDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Xin ZhangDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Lijuan MaDepartment of Clinical Laboratory, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China. malijuan@shouer.com.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBloodstream infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) in children pose a significant challenge to global public health and place tremendous pressure on clinical antibiotic treatment. A longitudinal retrospective study was designed to elucidate the clinical features, antibiotic resistance phenotypes, and molecular characteristics of CRKP isolated from bloodstream infections in children.

methodsCRKP strains were collected from blood cultures over an eight-year period (2018-2025) at a tertiary children's hospital in Beijing, China. Antimicrobial susceptibility testing and whole-genome sequencing (WGS) were performed to examine the resistance patterns and genetic diversity.

resultsCRKP bloodstream infections exhibited a distinct age-related pattern, with the highest incidence observed in infants younger than 3 months. Among the 91 isolates studied, none showed resistance to tigecycline or polymyxin B. The predominant carbapenemase genes identified were bla

conclusionPediatric CRKP bloodstream infections, predominantly affect young infants and are mediated primarily by bla

Indexed as

BacteremiaCarbapenem-Resistant EnterobacteriaceaeCarbapenemsKlebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial AgentsBacterial ProteinsBeijingbeta-LactamasesChildChild, PreschoolDrug Resistance, Multiple, BacterialFemaleHumansInfantInfant, NewbornAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsAntibiotic resistanceBloodstream infectionCarbapenem-resistant Klebsiella pneumoniaeChildren

Identifiers

PMID42443799
PMCPMC13647622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.