Evidence map›Paper›PMID 42443685›Full record

ArticleSurgical endoscopy2026

Hand-side matching in TOETVA: assessing feasibility and surgical outcomes through learning curve and propensity score-matched cohorts.

Xiaoyong Wen, Wu Li, Shiwei Zhou, Yu Mao, Zeyang Liu, Hui Li, Yulong Tang, Xiaohua Song, Xiaowei Peng, Peng Wu

Abstract read
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Xiaoyong Wen *Department of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Wu Li *Department of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Shiwei ZhouDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Yu MaoDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Zeyang LiuDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Hui LiDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Yulong TangDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Xiaohua SongDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Xiaowei PengDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China. pengxiaowei@hnca.org.cn.
Peng WuDepartment of Thyroid Surgery, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, No. 238Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China. wupeng@hnca.org.cn.

Funding

Health and Family Planning Commission of Hunan Province 20255241Health and Family Planning Commission of Hunan Province R2023115Health and Family Planning Commission of Hunan Province W20243236Science Fund for Distinguished Young Scholars of Hunan Province 2024ZK4141
6 · The paper itself

Abstract

objectiveTo address the lack of guidance for operating the non-dominant side in TOETVA by assessing whether non-dominant-hand TOETVA on the non-dominant side (left hand-left lobe) is a feasible strategy with similar surgical outcomes compared with the conventional dominant-hand approach (right hand-right lobe).

methodsThis is a single-center, single-surgeon retrospective cohort. Consecutive unilateral TOETVA cases (August 2016-August 2020) were included. Patients were grouped as NDH-TOETVA (left hand on the left lobe) or DH-TOETVA (right hand on the right lobe). Learning curves were segmented using cumulative sum (CUSUM) of operative time into Phase I (initial), Phase II (adaptation), and Phase III (mastery). Phase III outcomes were compared after 1:1 propensity score matching (PSM) on key covariates.

resultsCUSUM identified distinct phase boundaries: DH-TOETVA Phase I cases 1-13, Phase II 14-54, Phase III ≥ 55; NDH-TOETVA Phase I 1-17, Phase II 18-37, and Phase III ≥ 38. After PSM in Phase III, 176 patients were analyzed (NDH 88 cases, DH 88 cases). Post-match baseline characteristics were balanced. There were no significant differences between NDH and DH in operative time, estimated blood loss, central neck lymph nodes retrieved/positive, length of stay, postoperative drainage, and complications (P > 0.05).

conclusionsHand-side matching is a feasible strategy with compared surgical outcomes in TOETVA. Findings support incorporating this strategy and bilateral-hand training into standardized practice with phase-based, objective assessment. TRIAL REGISTRATION NUMBER: Chinese Clinical Trial Registry (UIN: ChiCTR2500097005, https://www.chictr.org.cn ), 2025.2.11.

Indexed as

Functional LateralityLearning CurveNatural Orifice Endoscopic SurgeryThyroidectomyFeasibility StudiesFemaleHumansMaleOperative TimePropensity ScoreRetrospective StudiesTreatment OutcomeCUSUMHand dominanceHand-side matchingLearning curvePropensity score matchingTransoral endoscopic thyroidectomy vestibular approach

Identifiers

PMID42443685
PMCPMC13582092

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.