ArticleJournal of imaging informatics in medicine2026
Pilot Study on Contrast-Enhanced CT-Based 3D Cascaded Segmentation of Hypopharyngeal Cancer and the Stability of the Extracted Radiomics Features.
Article in Journal of imaging informatics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hypopharyngeal cancer (HPC), a malignant head and neck tumor with poor prognosis, requires accurate pretreatment segmentation for surgical planning and radiomics analysis. However, no prior research has reported automated segmentation of hypopharyngeal cancer on CECT images or investigated the impact of such segmentation on radiomics features. This study developed a 3D cascaded HPCNet framework for automated HPC segmentation on CECT images and evaluated the stability of extracted radiomics features. Pretreatment CECT images of 180 patients with HPC were retrospectively acquired, and a 5-fold cross-validation strategy was adopted for dataset division. The cascaded HPCNet framework significantly outperformed the nnUNet in the segmentation of HPC, achieving the highest median DSC (0.793 vs. 0.768, p
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