Evidence map›Paper›PMID 42443422›Full record

ArticleAesthetic plastic surgery2026

A Cannula-Based Sequential Injection Protocol for Non-surgical Rhinoplasty in East Asian Patients.

Jiandong Ye, Xiancheng Wang, Kemin Yi, Pei Zou, Hao Liu

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jiandong YeDepartment of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Xiancheng WangDepartment of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China. wangxiancheng64@csu.edu.cn.ORCID http://orcid.org/0000-0001-8115-3962
Kemin YiDepartment of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Pei ZouDepartment of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Hao LiuDepartment of Plastic and Aesthetic Surgery, ShenZhen Mylike Cosmetic Hospital, Shenzhen, Guangdong, People's Republic of China. 51891044@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNon‑surgical rhinoplasty is increasingly popular for nasal augmentation in East Asian patients. However, a standardized, anatomy‑driven protocol for the sequential and layered correction of the nasal tip, dorsum, and glabellar complex-key aesthetic units in the Asian nose-is still lacking. MATERIALS AND

methodsIn this dual‑center retrospective study, 528 East Asian patients (490 females, 38 males; mean age 27.7 years) underwent non‑surgical rhinoplasty between 2020 and 2024. A high‑G' hyaluronic acid filler was injected via cannula in a predefined sequence: first, the nasal tip via fibrous septal deposition; followed by the dorsum and glabellar triangle. Outcomes were assessed using ·FACE‑Q and 3D facial scanning (MVS‑N1) preoperatively and at 9 months.

resultsThree‑dimensional analysis of the 426 patients who received the full three-site protocol showed significant improvements from baseline in nasal length (+ 2.62 mm), tip projection (+ 3.69 mm), nasolabial angle (+ 5.7°), and nasofrontal angle (- 9.4°) (all p < 0.001). FACE‑Q scores significantly improved across all 528 patients in satisfaction (+ 44.4 points), social function (+ 26.2), psychological well‑being (+ 28.1), and reduced distress (- 39.4) (all p < 0.001). No vascular complications occurred; 11 cases had transient erythema that resolved spontaneously or with conservative measures.

conclusionThe sequential "tip‑dorsum‑glabella" injection protocol, featuring a refined cannula‑based technique for fibrous septal tip augmentation, was associated with a low complication rate and significant short‑term improvements in patient‑reported and anthropometric outcomes in this retrospective analysis, suggesting that it is a clinically feasible approach for non‑surgical rhinoplasty in East Asian patients. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Dermal FillersHyaluronic AcidRhinoplastyAdultAsian PeopleCannulaEast Asian PeopleEstheticsFemaleHumansMaleNosePatient SatisfactionRetrospective StudiesTreatment OutcomeYoung AdultDermal FillersHyaluronic AcidCannulaFillerHyaluronic acidNon-surgical rhinoplastySequential injection

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.