Evidence map›Paper›PMID 42443202›Full record

ArticleNature communications2026

A plastoglobuli-localized enzyme links phenylalanine biosynthesis to translational homeostasis in maize.

Xing Huang, Yuwei Cao, Qiong Wang, Xingguo Wu, Yu Su, Changsheng Li, Jiaojiao Feng, Yujia Yang, Wenqin Wang, Yongrui Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xing Huang *State Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology & Ecology, Chinese Academy of Sciences, Shanghai, China.
Yuwei Cao *Shanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources Development, College of Life Science, Shanghai Normal University, Shanghai, China.
Qiong WangState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology & Ecology, Chinese Academy of Sciences, Shanghai, China.
Xingguo WuState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology & Ecology, Chinese Academy of Sciences, Shanghai, China.
Yu SuState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology & Ecology, Chinese Academy of Sciences, Shanghai, China.
Changsheng LiThe National Engineering Laboratory of Crop Stress Resistance Breeding, Anhui Agricultural University, Hefei, China.ORCID http://orcid.org/0000-0002-1397-6729
Jiaojiao FengShanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources Development, College of Life Science, Shanghai Normal University, Shanghai, China.
Yujia YangShanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources Development, College of Life Science, Shanghai Normal University, Shanghai, China.
Wenqin WangShanghai Key Laboratory of Plant Molecular Sciences, Shanghai Collaborative Innovation Center of Plant Germplasm Resources Development, College of Life Science, Shanghai Normal University, Shanghai, China. wang2021@shnu.edu.cn.ORCID http://orcid.org/0000-0001-6427-6338
Yongrui WuState Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology & Ecology, Chinese Academy of Sciences, Shanghai, China. yrwu@cemps.ac.cn.ORCID http://orcid.org/0000-0003-3822-0511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatic amino acids are essential precursors for numerous plant metabolites, with phenylalanine (Phe) forming the basis of the phenylpropanoid pathway. Here, we reveal a critical mechanism for Phe biosynthesis in maize, demonstrating that all seven arogenate dehydratases (ADTs) are specifically localized to plastoglobuli (PGs) in chloroplasts, and ADT2.2 shows high catalytic activity towards arogenate and prephenate. This discovery establishes PGs as a site for Phe synthesis. Genetic analysis confirms that only ADT2.2 is indispensable for plant and seed development, with its loss causing a severe Phe deficiency in seeds. This metabolic blockage directly reduced the tRNA

Indexed as

Hydro-LyasesPhenylalaninePlant ProteinsProtein BiosynthesisZea maysChloroplastsCodonGene Expression Regulation, PlantHomeostasisSeedsCodonHydro-LyasesPhenylalaninePlant Proteinspretyrosine dehydratase

Identifiers

PMID42443202
PMCPMC13527135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.