Evidence map›Paper›PMID 42442940›Full record

ArticleJournal of extracellular vesicles2026

EV-Checklist: AI-Powered Rapid Documentation for Enhancing Transparency and Accessibility of Extracellular Vesicle Research Data.

Rodolphe Poupardin, Martin Wolf, Antri Stefani, Gregor Fuhrmann, Dirk Strunk

Abstract read
In one paragraph

Article in Journal of extracellular vesicles, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rodolphe PoupardinCell Therapy Institute, Paracelsus Medical Private University, Salzburg, Austria.ORCID https://orcid.org/0000-0001-5195-5155
Martin WolfCell Therapy Institute, Paracelsus Medical Private University, Salzburg, Austria.ORCID https://orcid.org/0000-0002-4795-8086
Antri StefaniCell Therapy Institute, Paracelsus Medical Private University, Salzburg, Austria.ORCID https://orcid.org/0009-0008-9705-6794
Gregor FuhrmannDepartment of Biology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0000-0002-6688-5126
Dirk StrunkCell Therapy Institute, Paracelsus Medical Private University, Salzburg, Austria.ORCID https://orcid.org/0000-0003-1810-867X

Funding

European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program 945602European Union's Horizon Europe research and innovation program 101056712European Union's Horizon Europe research and innovation program 101080267European Union's Horizon Europe research and innovation program 101095635European Union's Horizon Europe research and innovation program 20102-F2001080-FPREuropean Union's Horizon Europe research and innovation program 20102-F2100572-FPREuropean Union's Horizon Europe research and innovation program 20102-F2400472European Union's Horizon Europe research and innovation program 20102/F2400948-FPREuropean Union's Horizon Europe research and innovation program P2506840Salzburger Landesregierung
6 · The paper itself

Abstract

Transition of extracellular vesicle (EV) research from basic discovery to clinical application raised hopes regarding diagnostic, therapeutic and prognostic progress. Rigorous reporting of experimental details is required to align the EV field with pharmaceutical quality standards. MISEV2023 recommendations encourage concise reporting but widespread adoption remains limited. Current reporting tools are time-consuming, and adherence declines despite rapidly growing number of EV studies. We therefore created EV-Checklist, a complementary digital tool that streamlines reporting and increases transparency. By uploading manuscript text, an AI-assisted algorithm automatically completes a checklist covering EV nomenclature, source, isolation, characterization and function. To ensure accuracy, users validate AI-generated entries before submission-ideally, gaps in reporting can be closed (e.g., missing particle/protein ratio). The resulting concise report can accompany manuscripts helping editors, reviewers and readers by presenting key methodological and results details at a glance. EV-Checklist complements existing comprehensive registries as 'fast-and-easy' tool enhancing clarity and accessibility of EV research data and may promote higher adherence to documentation standards. Adoption may be encouraged by journal endorsement to streamline the review process for compliant submissions, signalling adherence to MISEV2023 standards. EV-Checklist and an accompanying AI-assisted search tool (PMC EV Search), spanning over 45,700 open-access EV manuscripts, are publicly available at https://ev-zone.org/.

Indexed as

Artificial IntelligenceChecklistDocumentationExtracellular VesiclesBiomedical ResearchHumansartificial intelligence (AI)checklistdynamic reportingextracellular vesicles (EVs)MISEVresearch transparency

Identifiers

PMID42442940
PMCPMC13364539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.