Evidence map›Paper›PMID 42442799›Full record

ReviewBMJ global health2026

The impact of investments in health systems: a rapid review of computational models.

Deivis Nicolas Guzman-Tordecilla, Shivam Gupta, Shunsuke Mabuchi, Olga Bornemisza, Andres I Vecino-Ortiz

Abstract readReview
In one paragraph

Review in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deivis Nicolas Guzman-TordecillaHealth Systems Program, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-9419-7056
Shivam GuptaHealth Systems Program, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Shunsuke MabuchiThe Global Fund to Fight AIDS Tuberculosis and Malaria, Grand-Saconnex, Switzerland.
Olga BornemiszaThe Global Fund to Fight AIDS Tuberculosis and Malaria, Grand-Saconnex, Switzerland.
Andres I Vecino-OrtizHealth Systems Program, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA andres.vecino@gmail.com.ORCID 0000-0002-8089-2488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investments in health systems are essential for achieving effective sustainable and equitable health outcomes. However, national and global level stakeholders continue to grapple with how to quantify the impact of investments, its return of investment, and how to efficiently allocate health system inputs to improve health service delivery, health outputs and outcomes.This rapid review highlights the diverse computational models used to simulate investments in health systems strengthening. Our analysis revealed a range of methodologies, from agent-based simulations and dynamic computable general equilibrium models to structural equation models and the OneHealth Tool. Each model offers unique insights and has its strengths and limitations that need to be carefully considered for every scenario.A significant limitation across all models is the lack of external validation of the inputs and assumptions. The variability in data requirements and computational complexity also presents challenges in adapting these models to different contexts.To enhance the utility of these models, future research should focus on integrating ex-post impact evaluations and improving data collection to ensure accurate, context-specific inputs. Additionally, there is a need for better alignment between modelling results and policymaking processes to enhance the adoption and legitimacy among decision-makers of these tools.Overall, while current models provide valuable insights for planning and investment in health systems, addressing these limitations will be crucial for maximising their effectiveness and ensuring better-informed decision-making in health investments.

Indexed as

Computer SimulationDelivery of Health CareInvestmentsHumansDecision MakingHealth economicsMathematical modelling

Identifiers

PMID42442799
PMCPMC13365743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.