Evidence map›Paper›PMID 42442769›Full record

ReviewLower urinary tract symptoms2026

Ion Channels as Therapeutic Targets in Overactive Bladder: A Narrative Review of Mechanisms, Translational Evidence, and Current Gaps.

Berkay Demirçi, Gülsüm Helvacı, Elif Nur Barut, Seçkin Engin

Abstract readReview
In one paragraph

Review in Lower urinary tract symptoms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Berkay DemirçiDepartment of Pharmacology, Graduate School of Health Sciences, Karadeniz Technical University, Trabzon, Türkiye.ORCID https://orcid.org/0000-0003-2761-1517
Gülsüm HelvacıDepartment of Pharmacology, Graduate School of Health Sciences, Karadeniz Technical University, Trabzon, Türkiye.ORCID https://orcid.org/0009-0009-4029-473X
Elif Nur BarutDepartment of Pharmacology, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, Türkiye.ORCID https://orcid.org/0000-0003-3284-848X
Seçkin EnginDepartment of Pharmacology, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, Türkiye.ORCID https://orcid.org/0000-0002-1982-7820

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overactive bladder (OAB) is a prevalent syndrome whose first-line pharmacotherapy with antimuscarinics and β

Indexed as

Ion ChannelsUrinary Bladder, OveractiveAnimalsHumansMolecular Targeted TherapyTranslational Research, BiomedicalIon Channelsdetrusor overactivityion channelsoveractive bladderPIEZO channelsTRP channels

Identifiers

PMID42442769
PMCPMC13364484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.